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Chemmedchem
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October 25, 2018
Selective Optimization of Pranlukast to Farnesoid X Receptor Modulators
Simone Schierle, Jurema Schmidt, Astrid Kaiser, et al.
Bioorganic & Medicinal Chemistry
|
July 21, 2018
Structural optimization and in vitro profiling of N-phenylbenzamide-based farnesoid X receptor antagonists
Jurema Schmidt, Simone Schierle, Leonie Gellrich, et al.
ACS Pharmacology & Translational Science
|
April 16, 2021
Differential Therapeutic Effects of FXR Activation, sEH Inhibition, and Dual FXR/sEH Modulation in NASH in Diet-Induced Obese Mice
Moritz Helmstädter, Jurema Schmidt, Astrid Kaiser, et al.
Biochemical Pharmacology
|
May 27, 2019
A dual farnesoid X receptor/soluble epoxide hydrolase modulator treats non-alcoholic steatohepatitis in mice
Md Abdul Hye Khan, Jurema Schmidt, Anna Stavniichuk, et al.
Scientific Reports
|
October 2, 2015
NSAIDs Ibuprofen, Indometacin, and Diclofenac do not interact with Farnesoid X Receptor
Jurema Schmidt, Franca-Maria Klingler, Ewgenji Proschak, et al.
Journal of Medicinal Chemistry
|
June 24, 2021
Second-Generation Dual FXR/sEH Modulators with Optimized Pharmacokinetics
Moritz Helmstädter, Astrid Kaiser, Steffen Brunst, et al.
ACS Medicinal Chemistry Letters
|
February 19, 2021
A New FXR Ligand Chemotype with Agonist/Antagonist Switch
Moritz Helmstädter, Jan Vietor, Jana Sommer, et al.
Journal of Medicinal Chemistry
|
November 9, 2018
Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL)
David Heidenreich, Moses Moustakim, Jurema Schmidt, et al.
Scientific Reports
|
May 3, 2018
Allosteric modulation of the farnesoid X receptor by a small molecule
Matthias Gabler, Jan Kramer, Jurema Schmidt, et al.
Communications Chemistry
|
January 27, 2023
A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in mice
Pascal Heitel, Giuseppe Faudone, Moritz Helmstädter, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 15) with videos related to
Sort By:
Page
of 2
Chemmedchem
|
October 25, 2018
Selective Optimization of Pranlukast to Farnesoid X Receptor Modulators
Simone Schierle, Jurema Schmidt, Astrid Kaiser, et al.
Bioorganic & Medicinal Chemistry
|
July 21, 2018
Structural optimization and in vitro profiling of N-phenylbenzamide-based farnesoid X receptor antagonists
Jurema Schmidt, Simone Schierle, Leonie Gellrich, et al.
ACS Pharmacology & Translational Science
|
April 16, 2021
Differential Therapeutic Effects of FXR Activation, sEH Inhibition, and Dual FXR/sEH Modulation in NASH in Diet-Induced Obese Mice
Moritz Helmstädter, Jurema Schmidt, Astrid Kaiser, et al.
Biochemical Pharmacology
|
May 27, 2019
A dual farnesoid X receptor/soluble epoxide hydrolase modulator treats non-alcoholic steatohepatitis in mice
Md Abdul Hye Khan, Jurema Schmidt, Anna Stavniichuk, et al.
Scientific Reports
|
October 2, 2015
NSAIDs Ibuprofen, Indometacin, and Diclofenac do not interact with Farnesoid X Receptor
Jurema Schmidt, Franca-Maria Klingler, Ewgenji Proschak, et al.
Journal of Medicinal Chemistry
|
June 24, 2021
Second-Generation Dual FXR/sEH Modulators with Optimized Pharmacokinetics
Moritz Helmstädter, Astrid Kaiser, Steffen Brunst, et al.
ACS Medicinal Chemistry Letters
|
February 19, 2021
A New FXR Ligand Chemotype with Agonist/Antagonist Switch
Moritz Helmstädter, Jan Vietor, Jana Sommer, et al.
Journal of Medicinal Chemistry
|
November 9, 2018
Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL)
David Heidenreich, Moses Moustakim, Jurema Schmidt, et al.
Scientific Reports
|
May 3, 2018
Allosteric modulation of the farnesoid X receptor by a small molecule
Matthias Gabler, Jan Kramer, Jurema Schmidt, et al.
Communications Chemistry
|
January 27, 2023
A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in mice
Pascal Heitel, Giuseppe Faudone, Moritz Helmstädter, et al.
Page
of 2