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Journal of Medicinal Chemistry|January 24, 2020
Structure-Based Design and Identification of FT-2102 (Olutasidenib), a Potent Mutant-Selective IDH1 InhibitorJustin A Caravella, Jian Lin, R Bruce Diebold, et al.Bioorganic & Medicinal Chemistry Letters|January 25, 2011
Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthaleneJonathan Y Bass, Justin A Caravella, Lihong Chen, et al.Bioorganic & Medicinal Chemistry Letters|July 10, 2009
FXR agonist activity of conformationally constrained analogs of GW 4064Adwoa Akwabi-Ameyaw, Jonathan Y Bass, Richard D Caldwell, et al.Bioorganic & Medicinal Chemistry Letters|July 16, 2008
Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064Adwoa Akwabi-Ameyaw, Jonathan Y Bass, Richard D Caldwell, et al.The Journal of Cell Biology|January 28, 2021
The deubiquitylase USP9X controls ribosomal stallingAnne Clancy, Claire Heride, Adán Pinto-Fernández, et al.Journal of Medicinal Chemistry|April 29, 2026
Design of Cyclic Vinyl Sulfones as WRN Covalent Inhibitors from Noncovalent BindersJustin A Caravella, Angela V Toms, Nikolay Sitnikov, et al.Journal of Medicinal Chemistry|September 20, 2008
Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activityEsther Y Chao, Justin A Caravella, Mike A Watson, et al.Journal of Medicinal Chemistry|June 15, 2019
Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) InhibitorsJian Lin, Wei Lu, Justin A Caravella, et al.Journal of Medicinal Chemistry|August 19, 2005
Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structureMichael C Jaye, John A Krawiec, Nino Campobasso, et al.Nature|October 19, 2017
Molecular basis of USP7 inhibition by selective small-molecule inhibitorsAndrew P Turnbull, Stephanos Ioannidis, Wojciech W Krajewski, et al.Pageof 2