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Molecular Cell|November 29, 2023
Boveri and beyond: Chromothripsis and genomic instability from mitotic errorsAlice Mazzagatti, Justin L Engel, Peter LyBiorxiv : the Preprint Server for Biology|August 23, 2023
Non-homologous end joining shapes the genomic rearrangement landscape of chromothripsis from mitotic errorsQing Hu, Jose Espejo Valle-Inclan, Rashmi Dahiya, et al.Nature Communications|July 4, 2024
Non-homologous end joining shapes the genomic rearrangement landscape of chromothripsis from mitotic errorsQing Hu, Jose Espejo Valle-Inclán, Rashmi Dahiya, et al.Cell|August 24, 2024
The Fanconi anemia pathway induces chromothripsis and ecDNA-driven cancer drug resistanceJustin L Engel, Xiao Zhang, Mingming Wu, et al.Nature|May 10, 2023
Mitotic clustering of pulverized chromosomes from micronucleiYu-Fen Lin, Qing Hu, Alice Mazzagatti, et al.Bioorganic & Medicinal Chemistry Letters|May 2, 2025
Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitorScott Throner, Tianshu Feng, Jannik N Andersen, et al.Molecular Cancer Therapeutics|May 6, 2025
CRISPR screens identify POLB as a synthetic lethal enhancer of PARP inhibition exclusively in BRCA-mutated tumorsKatherine Lazarides, Justin L Engel, Michele Meseonznik, et al.Biorxiv : the Preprint Server for Biology|July 17, 2026
A single chromosome 3p break initiates clear cell renal cell carcinoma evolutionRashmi Dahiya, Ianthe A E M van Belzen, Chengheng Liao, et al.Molecular Cancer Therapeutics|October 13, 2022
Ubiquitinated PCNA Drives USP1 Synthetic Lethality in CancerAntoine Simoneau, Justin L Engel, Madhavi Bandi, et al.Cancer Research|September 7, 2022
VRK1 Is a Synthetic-Lethal Target in VRK2-Deficient GlioblastomaJulie A Shields, Samuel R Meier, Madhavi Bandi, et al.Pageof 1