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American Journal of Physiology. Lung Cellular and Molecular Physiology|November 23, 2014
Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertensionHaiyang Tang, Jiwang Chen, Dustin R Fraidenburg, et al.International Journal of Molecular Sciences|December 11, 2022
Sphingosine Kinase 1 Deficiency in Smooth Muscle Cells Protects against Hypoxia-Mediated Pulmonary Hypertension via YAP1 SignalingJiwang Chen, Angelia Lockett, Shuangping Zhao, et al.Molecular Metabolism|October 1, 2016
Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolismCarles Lerin, Allison B Goldfine, Tanner Boes, et al.American Journal of Respiratory and Critical Care Medicine|September 3, 2014
The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertensionJiwang Chen, Haiyang Tang, Justin R Sysol, et al.Circulation|February 17, 2017
Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial HypertensionJiwang Chen, Justin R Sysol, Sunit Singla, et al.Proceedings of the National Academy of Sciences of the United States of America|July 31, 2013
Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemiaIrini Manoli, Justin R Sysol, Lingli Li, et al.Nature Genetics|August 16, 2011
Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduriaJennifer L Sloan, Jennifer J Johnston, Irini Manoli, et al.JCI Insight|January 25, 2024
Lipodystrophy in methylmalonic acidemia associated with elevated FGF21 and abnormal methylmalonylationIrini Manoli, Justin R Sysol, PamelaSara E Head, et al.JCI Insight|December 7, 2018
FGF21 underlies a hormetic response to metabolic stress in methylmalonic acidemiaIrini Manoli, Justin R Sysol, Madeline W Epping, et al.Pageof 2