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Angewandte Chemie (International Ed. in English)
|
February 6, 2003
Design and application of an alpha-helix-mimetic scaffold based on an oligoamide-foldamer strategy: antagonism of the Bak BH3/Bcl-xL complex
Justin T Ernst, Jorge Becerril, Hyung Soon Park, et al.
AIDS Research and Human Retroviruses
|
October 25, 2002
XTT formazan widely used to detect cell viability inhibits HIV type 1 infection in vitro by targeting gp41
Qian Zhao, Justin T Ernst, Andrew D Hamilton, et al.
Molecular Diversity
|
June 24, 2004
Protein recognition using synthetic surface-targeted agents
Rishi Jain, Justin T Ernst, Olaf Kutzki, et al.
Angewandte Chemie (International Ed. in English)
|
December 20, 2002
Design of a protein surface antagonist based on alpha-helix mimicry: inhibition of gp41 assembly and viral fusion
Justin T Ernst, Olaf Kutzki, Asim K Debnath, et al.
Journal of the American Chemical Society
|
October 3, 2002
Development of a potent Bcl-x(L) antagonist based on alpha-helix mimicry
Olaf Kutzki, Hyung Soon Park, Justin T Ernst, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 17, 2013
Correlation between chemotype-dependent binding conformations of HSP90α/β and isoform selectivity-Implications for the structure-based design of HSP90α/β selective inhibitors for treating neurodegenerative diseases
Justin T Ernst, Michael Liu, Harmon Zuccola, et al.
Journal of the American Chemical Society
|
July 21, 2005
Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL
Hang Yin, Gui-In Lee, Kristine A Sedey, et al.
Organic Letters
|
August 19, 2020
Strategic Diastereoselective C1 Functionalization in the Aza-Rocaglamide Scaffold toward Natural Product-Inspired eIF4A Inhibitors
Christian Nilewski, Theodore D Michels, Alan X Xiang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 6, 2021
1-Aminomethyl SAR in a novel series of flavagline-inspired eIF4A inhibitors: Effects of amine substitution on cell potency and in vitro PK properties
Christian Nilewski, Theodore D Michels, Garrick K Packard, et al.
Journal of Medicinal Chemistry
|
March 29, 2014
Identification of novel HSP90α/β isoform selective inhibitors using structure-based drug design. demonstration of potential utility in treating CNS disorders such as Huntington's disease
Justin T Ernst, Timothy Neubert, Michael Liu, et al.
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Search research articles
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Showing results (1-10 of 15) with videos related to
Sort By:
Page
of 2
Angewandte Chemie (International Ed. in English)
|
February 6, 2003
Design and application of an alpha-helix-mimetic scaffold based on an oligoamide-foldamer strategy: antagonism of the Bak BH3/Bcl-xL complex
Justin T Ernst, Jorge Becerril, Hyung Soon Park, et al.
AIDS Research and Human Retroviruses
|
October 25, 2002
XTT formazan widely used to detect cell viability inhibits HIV type 1 infection in vitro by targeting gp41
Qian Zhao, Justin T Ernst, Andrew D Hamilton, et al.
Molecular Diversity
|
June 24, 2004
Protein recognition using synthetic surface-targeted agents
Rishi Jain, Justin T Ernst, Olaf Kutzki, et al.
Angewandte Chemie (International Ed. in English)
|
December 20, 2002
Design of a protein surface antagonist based on alpha-helix mimicry: inhibition of gp41 assembly and viral fusion
Justin T Ernst, Olaf Kutzki, Asim K Debnath, et al.
Journal of the American Chemical Society
|
October 3, 2002
Development of a potent Bcl-x(L) antagonist based on alpha-helix mimicry
Olaf Kutzki, Hyung Soon Park, Justin T Ernst, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 17, 2013
Correlation between chemotype-dependent binding conformations of HSP90α/β and isoform selectivity-Implications for the structure-based design of HSP90α/β selective inhibitors for treating neurodegenerative diseases
Justin T Ernst, Michael Liu, Harmon Zuccola, et al.
Journal of the American Chemical Society
|
July 21, 2005
Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL
Hang Yin, Gui-In Lee, Kristine A Sedey, et al.
Organic Letters
|
August 19, 2020
Strategic Diastereoselective C1 Functionalization in the Aza-Rocaglamide Scaffold toward Natural Product-Inspired eIF4A Inhibitors
Christian Nilewski, Theodore D Michels, Alan X Xiang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 6, 2021
1-Aminomethyl SAR in a novel series of flavagline-inspired eIF4A inhibitors: Effects of amine substitution on cell potency and in vitro PK properties
Christian Nilewski, Theodore D Michels, Garrick K Packard, et al.
Journal of Medicinal Chemistry
|
March 29, 2014
Identification of novel HSP90α/β isoform selective inhibitors using structure-based drug design. demonstration of potential utility in treating CNS disorders such as Huntington's disease
Justin T Ernst, Timothy Neubert, Michael Liu, et al.
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of 2