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Cancers
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January 10, 2026
Unraveling Resistance Mechanisms to Gαq Pathway Inhibition in Uveal Melanoma: Insights from Signaling-Activation Library Screening
Simone Lubrano, Rodolfo Daniel Cervantes-Villagrana, Nadia Arang, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
September 2, 2015
Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression
Justine S Paradis, Stevenson Ly, Élodie Blondel-Tepaz, et al.
Nature Communications
|
July 17, 2014
A biosensor to monitor dynamic regulation and function of tumour suppressor PTEN in living cells
Evelyne Lima-Fernandes, Stanislas Misticone, Cédric Boularan, et al.
Nature Communications
|
November 12, 2022
Computationally designed GPCR quaternary structures bias signaling pathway activation
Justine S Paradis, Xiang Feng, Brigitte Murat, et al.
Cells
|
April 13, 2023
Effect of the Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulator Dipraglurant on Motor and Non-Motor Symptoms of Parkinson's Disease
Mark P Epping-Jordan, Françoise Girard, Anne-Sophie Bessis, et al.
Nature Communications
|
April 19, 2017
A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling
Alexandre Beautrait, Justine S Paradis, Brandon Zimmerman, et al.
The Journal of Biological Chemistry
|
September 29, 2023
Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor
Valeria Burghi, Justine S Paradis, Adam Officer, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
February 11, 2021
Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for <i>GNAQ</i>-Driven Uveal Melanoma
Justine S Paradis, Monica Acosta, Robert Saddawi-Konefka, et al.
Oncogene
|
March 2, 2021
The RanBP2/RanGAP1-SUMO complex gates β-arrestin2 nuclear entry to regulate the Mdm2-p53 signaling axis
Elodie Blondel-Tepaz, Marie Leverve, Badr Sokrat, et al.
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of 1
Search research articles
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Showing results (1-10 of 9) with videos related to
Sort By:
Page
of 1
Cancers
|
January 10, 2026
Unraveling Resistance Mechanisms to Gαq Pathway Inhibition in Uveal Melanoma: Insights from Signaling-Activation Library Screening
Simone Lubrano, Rodolfo Daniel Cervantes-Villagrana, Nadia Arang, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
September 2, 2015
Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression
Justine S Paradis, Stevenson Ly, Élodie Blondel-Tepaz, et al.
Nature Communications
|
July 17, 2014
A biosensor to monitor dynamic regulation and function of tumour suppressor PTEN in living cells
Evelyne Lima-Fernandes, Stanislas Misticone, Cédric Boularan, et al.
Nature Communications
|
November 12, 2022
Computationally designed GPCR quaternary structures bias signaling pathway activation
Justine S Paradis, Xiang Feng, Brigitte Murat, et al.
Cells
|
April 13, 2023
Effect of the Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulator Dipraglurant on Motor and Non-Motor Symptoms of Parkinson's Disease
Mark P Epping-Jordan, Françoise Girard, Anne-Sophie Bessis, et al.
Nature Communications
|
April 19, 2017
A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling
Alexandre Beautrait, Justine S Paradis, Brandon Zimmerman, et al.
The Journal of Biological Chemistry
|
September 29, 2023
Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor
Valeria Burghi, Justine S Paradis, Adam Officer, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
February 11, 2021
Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for <i>GNAQ</i>-Driven Uveal Melanoma
Justine S Paradis, Monica Acosta, Robert Saddawi-Konefka, et al.
Oncogene
|
March 2, 2021
The RanBP2/RanGAP1-SUMO complex gates β-arrestin2 nuclear entry to regulate the Mdm2-p53 signaling axis
Elodie Blondel-Tepaz, Marie Leverve, Badr Sokrat, et al.
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of 1