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International Journal for Parasitology|January 8, 2013
The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotypeJustyna Rzepecka, Ivonne Siebeke, Jennifer C Coltherd, et al.
Nature Immunology|March 2, 2011
The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88Padmam Puneet, Mairi A McGrath, Hwee Kee Tay, et al.
Journal of Medicinal Chemistry|November 16, 2013
Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritisLamyaa Al-Riyami, Miguel A Pineda, Justyna Rzepecka, et al.
Biomedicines|August 28, 2025
An Immunomodulating Peptide with Potential to Promote Anticancer Immunity Without Compromising Immune ToleranceMichael Agrez, Christopher Chandler, Amanda L Johnson, et al.
International Journal for Parasitology|June 15, 2014
Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy propertiesJustyna Rzepecka, Michelle L Coates, Moninder Saggar, et al.
Scientific Reports|November 5, 2024
A novel immunomodulating peptide with potential to complement oligodeoxynucleotide-mediated adjuvanticity in vaccination strategiesMichael Agrez, Christopher Chandler, Kristofer J Thurecht, et al.
Journal of Autoimmunity|May 16, 2015
Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasomeJustyna Rzepecka, Miguel A Pineda, Lamyaa Al-Riyami, et al.
Scientific Reports|November 13, 2023
An immunomodulating peptide with potential to suppress tumour growth and autoimmunityMichael Agrez, Christopher Chandler, Kristofer J Thurecht, et al.
Scientific Reports|July 20, 2023
An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damageMichael Agrez, Mark Stephen Rybchyn, Warusavithana Gunawardena Manori De Silva, et al.
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