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Protein Engineering
|
March 1, 1994
A sound basis for pH-dependent kinetic studies on enzymes
K Brocklehurst
The Biochemical Journal
|
September 1, 1979
The equilibrium assumption is valid for the kinetic treatment of most time-dependent protein-modification reactions
K Brocklehurst
The Biochemical Journal
|
April 1, 1977
Evolution of enzyme catalytic power. Characteristics of optimal catalysis evaluated for the simplest plausible kinetic model
K Brocklehurst
Nature
|
May 31, 1990
Papain and related proteins
K Brocklehurst
Methods in Enzymology
|
January 1, 1982
Two-protonic-state electrophiles as probes of enzyme mechanisms
K Brocklehurst
The International Journal of Biochemistry
|
January 1, 1979
Specific covalent modification of thiols: applications in the study of enzymes and other biomolecules
K Brocklehurst
The Biochemical Journal
|
April 15, 1985
Preparation of cathepsins B and H by covalent chromatography and characterization of their catalytic sites by reaction with a thiol-specific two-protonic-state reactivity probe. Kinetic study of cathepsins B and H extending into alkaline media and a rapid spectroscopic titration of cathepsin H at pH 3-4
F Willenbrock, K Brocklehurst
The Biochemical Journal
|
May 1, 1973
Reactions of papain and of low-molecular-weight thiols with some aromatic disulphides. 2,2'-Dipyridyl disulphide as a convenient active-site titrant for papain even in the presence of other thiols
K Brocklehurst, G Little
The Biochemical Journal
|
April 15, 1985
A general framework of cysteine-proteinase mechanism deduced from studies on enzymes with structurally different analogous catalytic-site residues Asp-158 and -161 (papain and actinidin), Gly-196 (cathepsin B) and Asn-165 (cathepsin H). Kinetic studies up to pH 8 of the hydrolysis of N-alpha-benzyloxycarbonyl-L-arginyl-L-arginine 2-naphthylamide catalysed by cathepsin B and of L-arginine 2-naphthylamide catalysed by cathepsin H
F Willenbrock, K Brocklehurst
FEBS Letters
|
July 29, 1970
A novel reactivity of papain and a convenient active site titration in the presence of other thiols
K Brocklehurst, G Little
Page
of 15
Search research articles
Search
Showing results (1-10 of 145) with videos related to
Sort By:
Page
of 15
Protein Engineering
|
March 1, 1994
A sound basis for pH-dependent kinetic studies on enzymes
K Brocklehurst
The Biochemical Journal
|
September 1, 1979
The equilibrium assumption is valid for the kinetic treatment of most time-dependent protein-modification reactions
K Brocklehurst
The Biochemical Journal
|
April 1, 1977
Evolution of enzyme catalytic power. Characteristics of optimal catalysis evaluated for the simplest plausible kinetic model
K Brocklehurst
Nature
|
May 31, 1990
Papain and related proteins
K Brocklehurst
Methods in Enzymology
|
January 1, 1982
Two-protonic-state electrophiles as probes of enzyme mechanisms
K Brocklehurst
The International Journal of Biochemistry
|
January 1, 1979
Specific covalent modification of thiols: applications in the study of enzymes and other biomolecules
K Brocklehurst
The Biochemical Journal
|
April 15, 1985
Preparation of cathepsins B and H by covalent chromatography and characterization of their catalytic sites by reaction with a thiol-specific two-protonic-state reactivity probe. Kinetic study of cathepsins B and H extending into alkaline media and a rapid spectroscopic titration of cathepsin H at pH 3-4
F Willenbrock, K Brocklehurst
The Biochemical Journal
|
May 1, 1973
Reactions of papain and of low-molecular-weight thiols with some aromatic disulphides. 2,2'-Dipyridyl disulphide as a convenient active-site titrant for papain even in the presence of other thiols
K Brocklehurst, G Little
The Biochemical Journal
|
April 15, 1985
A general framework of cysteine-proteinase mechanism deduced from studies on enzymes with structurally different analogous catalytic-site residues Asp-158 and -161 (papain and actinidin), Gly-196 (cathepsin B) and Asn-165 (cathepsin H). Kinetic studies up to pH 8 of the hydrolysis of N-alpha-benzyloxycarbonyl-L-arginyl-L-arginine 2-naphthylamide catalysed by cathepsin B and of L-arginine 2-naphthylamide catalysed by cathepsin H
F Willenbrock, K Brocklehurst
FEBS Letters
|
July 29, 1970
A novel reactivity of papain and a convenient active site titration in the presence of other thiols
K Brocklehurst, G Little
Page
of 15