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K F Koehler

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Drug Design and Discovery|January 1, 1995

Development of a comprehensive pharmacophore model for the benzodiazepine receptorW Zhang, K F Koehler, P Zhang, et al.

Journal of Medicinal Chemistry|March 18, 1994

Synthesis of benzo-fused benzodiazepines employed as probes of the agonist pharmacophore of benzodiazepine receptorsW Zhang, K F Koehler, B Harris, et al.

Life Sciences|January 1, 1991

Synthetic and computer assisted analysis of the pharmacophore for agonists at benzodiazepine receptorsH Diaz-Arauzo, K F Koehler, T J Hagen, et al.

The Journal of Biological Chemistry|April 5, 2000

Functional probing of the human glucocorticoid receptor steroid-interacting surface by site-directed mutagenesis. Gln-642 plays an important role in steroid recognition and bindingU Lind, P Greenidge, M Gillner, et al.

Proceedings of the National Academy of Sciences of the United States of America|June 1, 1986

Analysis of the phorbol ester pharmacophore on protein kinase C as a guide to the rational design of new classes of analogsP A Wender, K F Koehler, N A Sharkey, et al.

Journal of Chemical Information and Computer Sciences|July 1, 1997

Molecular design using the minireceptor conceptJ M Jansen, K F Koehler, M H Hedberg, et al.

Journal of Medicinal Chemistry|June 25, 1993

Synthetic and computer-assisted analysis of the structural requirements for selective, high-affinity ligand binding to diazepam-insensitive benzodiazepine receptorsG Wong, K F Koehler, P Skolnick, et al.

Proceedings of the National Academy of Sciences of the United States of America|October 1, 1988

Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase CP A Wender, C M Cribbs, K F Koehler, et al.

Journal of Medicinal Chemistry|October 30, 1992

Predictive binding of beta-carboline inverse agonists and antagonists via the CoMFA/GOLPE approachM S Allen, A J LaLoggia, L J Dorn, et al.

Journal of Medicinal Chemistry|September 1, 1990

Synthetic and computer-assisted analyses of the pharmacophore for the benzodiazepine receptor inverse agonist siteM S Allen, Y C Tan, M L Trudell, et al.

Pageof 1

Search research articles

Showing results (1-10 of 10) with videos related to

Sort By:

Pageof 1

Drug Design and Discovery|January 1, 1995

Development of a comprehensive pharmacophore model for the benzodiazepine receptorW Zhang, K F Koehler, P Zhang, et al.

Journal of Medicinal Chemistry|March 18, 1994

Synthesis of benzo-fused benzodiazepines employed as probes of the agonist pharmacophore of benzodiazepine receptorsW Zhang, K F Koehler, B Harris, et al.

Life Sciences|January 1, 1991

Synthetic and computer assisted analysis of the pharmacophore for agonists at benzodiazepine receptorsH Diaz-Arauzo, K F Koehler, T J Hagen, et al.

The Journal of Biological Chemistry|April 5, 2000

Functional probing of the human glucocorticoid receptor steroid-interacting surface by site-directed mutagenesis. Gln-642 plays an important role in steroid recognition and bindingU Lind, P Greenidge, M Gillner, et al.

Proceedings of the National Academy of Sciences of the United States of America|June 1, 1986

Analysis of the phorbol ester pharmacophore on protein kinase C as a guide to the rational design of new classes of analogsP A Wender, K F Koehler, N A Sharkey, et al.

Journal of Chemical Information and Computer Sciences|July 1, 1997

Molecular design using the minireceptor conceptJ M Jansen, K F Koehler, M H Hedberg, et al.

Journal of Medicinal Chemistry|June 25, 1993

Synthetic and computer-assisted analysis of the structural requirements for selective, high-affinity ligand binding to diazepam-insensitive benzodiazepine receptorsG Wong, K F Koehler, P Skolnick, et al.

Proceedings of the National Academy of Sciences of the United States of America|October 1, 1988

Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase CP A Wender, C M Cribbs, K F Koehler, et al.

Journal of Medicinal Chemistry|October 30, 1992

Predictive binding of beta-carboline inverse agonists and antagonists via the CoMFA/GOLPE approachM S Allen, A J LaLoggia, L J Dorn, et al.

Journal of Medicinal Chemistry|September 1, 1990

Synthetic and computer-assisted analyses of the pharmacophore for the benzodiazepine receptor inverse agonist siteM S Allen, Y C Tan, M L Trudell, et al.

Pageof 1