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Journal of Pharmacokinetics and Pharmacodynamics|July 27, 2001
Efficient screening of covariates in population models using Wald's approximation to the likelihood ratio testK G Kowalski, M M HutmacherStatistics in Medicine|January 3, 2001
Design evaluation for a population pharmacokinetic study using clinical trial simulations: a case studyK G Kowalski, M M HutmacherClinical Pharmacology and Therapeutics|September 21, 2007
Modeling and simulation to support dose selection and clinical development of SC-75416, a selective COX-2 inhibitor for the treatment of acute and chronic painK G Kowalski, S Olson, A E Remmers, et al.Computer Methods and Programs in Biomedicine|February 14, 1994
An algorithm for estimating the terminal half-life in pharmacokinetic studiesK G KowalskiCPT: Pharmacometrics & Systems Pharmacology|July 31, 2015
Evaluating the Use of Linear Mixed-Effect Models for Inference of the Concentration-QTc Slope Estimate as a Surrogate for a Biological QTc ModelY Huh, M M HutmacherJournal of Pharmacokinetics and Biopharmaceutics|June 1, 1995
A semicompartmental modeling approach for pharmacodynamic data assessmentK G Kowalski, A KarimJournal of Pharmacokinetics and Pharmacodynamics|September 20, 2012
Modeling of Functional Assessment Questionnaire (FAQ) as continuous bounded data from the ADNI databaseK Ito, M M Hutmacher, B W CorriganClinical Pharmacology and Therapeutics|November 26, 2010
Comparison of QTc data analysis methods recommended by the ICH E14 guidance and exposure-response analysis: case study of a thorough QT study of asenapineS Chapel, M M Hutmacher, H Bockbrader, et al.Journal of Clinical Pharmacology|May 1, 1989
Effects of food and antacid on oral absorption of misoprostol, a synthetic prostaglandin E1 analogA Karim, L F Rozek, M E Smith, et al.Clinical Pharmacology and Therapeutics|May 25, 2007
Model-based drug developmentR L Lalonde, K G Kowalski, M M Hutmacher, et al.Pageof 2