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Biorxiv : the Preprint Server for Biology|February 27, 2026
A universal platform for simultaneous TCRα/β removal enables safer and more potent TCR therapies and autoimmune modelingGiorgia Zanetti, Mateusz Legut, Austin Chen, et al.The Journal of Clinical Investigation|May 17, 2016
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivityDavid K Cole, Anna M Bulek, Garry Dolton, et al.Journal of Immunological Methods|August 5, 2008
Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramersJ Joseph Melenhorst, Phillip Scheinberg, Pratip K Chattopadhyay, et al.Proceedings of the National Academy of Sciences of the United States of America|July 17, 2021
CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptorMathew Clement, Lea Knezevic, Tamsin Dockree, et al.Journal of Immunology (Baltimore, Md. : 1950)|March 2, 2010
MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLsLinda Wooldridge, Mathew Clement, Anna Lissina, et al.Diabetes|September 25, 2014
β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposureAnia Skowera, Kristin Ladell, James E McLaren, et al.Journal of Immunology (Baltimore, Md. : 1950)|December 3, 2014
Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRsKatie Tungatt, Valentina Bianchi, Michael D Crowther, et al.Immunology and Cell Biology|February 6, 2016
Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptorsBarbara Szomolay, Jie Liu, Paul E Brown, et al.Nature Medicine|November 14, 2017
Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignanciesPaul M Maciocia, Patrycja A Wawrzyniecka, Brian Philip, et al.The Journal of Biological Chemistry|May 24, 2013
T-cell receptor specificity maintained by altered thermodynamicsFlorian Madura, Pierre J Rizkallah, Kim M Miles, et al.Pageof 33