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American Heart Journal|November 14, 2025
Rationale for and design of the REsolution of LEft VENTricular thrombus (RELEVENT) TrialGraham S Hillis, Jarryd S K Walker, Thomas Gilbert, et al.Journal of Neurology, Neurosurgery, and Psychiatry|November 7, 2019
Genetic and immunopathological analysis of CHCHD10 in Australian amyotrophic lateral sclerosis and frontotemporal dementia and transgenic TDP-43 miceEmily P McCann, Jennifer A Fifita, Natalie Grima, et al.Bioorganic & Medicinal Chemistry Letters|June 23, 2009
Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring systemRobert O Hughes, John K Walker, Jerry W Cubbage, et al.Journal of Medicinal Chemistry|March 4, 2010
Design, synthesis, and biological evaluation of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a potent, orally active, brain penetrant inhibitor of phosphodiesterase 5 (PDE5)Robert O Hughes, D Joseph Rogier, E Jon Jacobsen, et al.Nature Communications|January 20, 2025
Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosomeHugh D Goold, Heinrich Kroukamp, Paige E Erpf, et al.Cell Genomics|November 29, 2023
Parallel laboratory evolution and rational debugging reveal genomic plasticity to <i>S. cerevisiae</i> synthetic chromosome XIV defectsThomas C Williams, Heinrich Kroukamp, Xin Xu, et al.Bioorganic & Medicinal Chemistry Letters|June 7, 2011
Design, synthesis and activity of a potent, selective series of N-aryl pyridinone inhibitors of p38 kinaseShaun R Selness, Terri L Boehm, John K Walker, et al.Cell|November 9, 2023
Design, construction, and functional characterization of a tRNA neochromosome in yeastDaniel Schindler, Roy S K Walker, Shuangying Jiang, et al.Journal of Pediatric Surgery|March 19, 2019
Development of a multi-institutional registry for children with operative congenital lung malformationsShaun M Kunisaki, Jacqueline M Saito, Mary E Fallat, et al.Bioorganic & Medicinal Chemistry Letters|June 7, 2011
Discovery of PH-797804, a highly selective and potent inhibitor of p38 MAP kinaseShaun R Selness, Rajesh V Devraj, Balekudru Devadas, et al.Pageof 146