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Cell|June 4, 2013
53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactionsElsa Callen, Michela Di Virgilio, Michael J Kruhlak, et al.
International Journal of Cancer|May 4, 2023
KMT2D links TGF-β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticityShuang Lu, Hong Sun Kim, Yubo Cao, et al.
Nature|August 1, 2014
DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrierMargarida A Santos, Robert B Faryabi, Aysegul V Ergen, et al.
The Journal of Biological Chemistry|May 28, 2026
KMT2D depletion promotes KRAS-induced pancreatic carcinogenesis independent of TP53Ezequiel J Tolosa, Glancis L Raja Arul, Ashley N Sigafoos, et al.
Nature Communications|November 26, 2025
Enhancer regulator MLL4 controls skeletal muscle metabolic efficiency by limiting AMPK-mediated fuel catabolismLikun Yang, Lin Liu, Wen Wang, et al.
Nature Medicine|September 15, 2015
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma developmentAna Ortega-Molina, Isaac W Boss, Andres Canela, et al.
Nature|July 23, 2016
Replication fork stability confers chemoresistance in BRCA-deficient cellsArnab Ray Chaudhuri, Elsa Callen, Xia Ding, et al.
Nature Genetics|January 13, 2025
Loss of Kmt2c or Kmt2d primes urothelium for tumorigenesis and redistributes KMT2A-menin to bivalent promotersNaitao Wang, Mohini R Pachai, Dan Li, et al.
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