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Molecular Pharmacology|May 12, 2009
Functional importance of a structurally distinct homodimeric complex of the family B G protein-coupled secretin receptorFan Gao, Kaleeckal G Harikumar, Maoqing Dong, et al.
Biochemical Pharmacology|February 5, 2021
Discovery of small molecule positive allosteric modulators of the secretin receptorDaniela G Dengler, Kaleeckal G Harikumar, Sirkku Pollari, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|March 7, 2014
Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross-class GPCR heterocomplexLeo T O Lee, Stephanie Y L Ng, Jessica Y S Chu, et al.
Plos One|March 23, 2012
Modulation of β-catenin signaling by glucagon receptor activationJiyuan Ke, Chenghai Zhang, Kaleeckal G Harikumar, et al.
Genes & Development|May 27, 2017
Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerizationZachary J DeBruine, Jiyuan Ke, Kaleeckal G Harikumar, et al.
The Journal of Biological Chemistry|June 12, 2013
Molecular basis for benzodiazepine agonist action at the type 1 cholecystokinin receptorKaleeckal G Harikumar, Erin E Cawston, Polo C H Lam, et al.
Communications Biology|July 2, 2025
Mechanistic insights from the atomic-level quaternary structure of short-lived GPCR oligomers of the human secretin receptor in live cellsMichael R Stoneman, Thomas D Killeen, Koki Yokoi, et al.
SLAS Discovery : Advancing Life Sciences R & D|August 5, 2020
Development of a Testing Funnel for Identification of Small-Molecule Modulators Targeting Secretin ReceptorsDaniela G Dengler, Qing Sun, John Holleran, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 24, 2012
Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allosteryKaleeckal G Harikumar, Denise Wootten, Delia I Pinon, et al.
Frontiers in Endocrinology|December 24, 2021
Discovery of a Positive Allosteric Modulator of Cholecystokinin Action at CCK1R in Normal and Elevated CholesterolKaleeckal G Harikumar, Thomas Coudrat, Aditya J Desai, et al.
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