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Genes & Development|November 5, 2013
Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complexJiyuan Ke, Kaleeckal G Harikumar, Clara Erice, et al.The Journal of Biological Chemistry|April 3, 2012
Molecular basis for binding and subtype selectivity of 1,4-benzodiazepine antagonist ligands of the cholecystokinin receptorErin E Cawston, Polo C H Lam, Kaleeckal G Harikumar, et al.Plos Biology|June 4, 2021
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivityJesse I Mobbs, Matthew J Belousoff, Kaleeckal G Harikumar, et al.Biochemical Pharmacology|March 29, 2020
Rational development of a high-affinity secretin receptor antagonistMaoqing Dong, Kaleeckal G Harikumar, Sweta R Raval, et al.SLAS Discovery : Advancing Life Sciences R & D|August 9, 2024
Structure-activity relationships of thiadiazole agonists of the human secretin receptorRobert Ardecky, Daniela G Dengler, Kaleeckal G Harikumar, et al.Plos Biology|July 31, 2024
Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein couplingKaleeckal G Harikumar, Peishen Zhao, Brian P Cary, et al.Nature Communications|August 20, 2020
Structure and dynamics of the active Gs-coupled human secretin receptorMaoqing Dong, Giuseppe Deganutti, Sarah J Piper, et al.Nature Methods|March 9, 2021
Single-molecule FRET imaging of GPCR dimers in living cellsWesley B Asher, Peter Geggier, Michael D Holsey, et al.Science (New York, N.Y.)|August 26, 2021
Structure of an AMPK complex in an inactive, ATP-bound stateYan Yan, Somnath Mukherjee, Kaleeckal G Harikumar, et al.Nature|August 24, 2018
Crystal structure of the Frizzled 4 receptor in a ligand-free stateShifan Yang, Yiran Wu, Ting-Hai Xu, et al.Pageof 8