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Cancer Research|April 22, 2010
Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interfaceKalyan C Nannuru, Mitsuru Futakuchi, Michelle L Varney, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|March 19, 2009
Small-molecule antagonists for CXCR2 and CXCR1 inhibit human melanoma growth by decreasing tumor cell proliferation, survival, and angiogenesisSeema Singh, Anguraj Sadanandam, Kalyan C Nannuru, et al.
Cancer Science|November 29, 2008
Transforming growth factor-beta signaling at the tumor-bone interface promotes mammary tumor growth and osteoclast activationMitsuru Futakuchi, Kalyan C Nannuru, Michelle L Varney, et al.
Clinical & Experimental Metastasis|July 11, 2009
Enhanced expression and shedding of receptor activator of NF-kappaB ligand during tumor-bone interaction potentiates mammary tumor-induced osteolysisKalyan C Nannuru, Mitsuru Futakuchi, Anguraj Sadanandam, et al.
Bone|June 20, 2020
Activin A does not drive post-traumatic heterotopic ossificationCharles Hwang, Chase A Pagani, Nanditha Das, et al.
The Journal of Clinical Investigation|May 5, 2022
Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1Senem Aykul, Lily Huang, Lili Wang, et al.
Science Translational Medicine|September 4, 2015
ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin ASarah J Hatsell, Vincent Idone, Dana M Alessi Wolken, et al.
Elife|June 10, 2020
Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loopSenem Aykul, Richard A Corpina, Erich J Goebel, et al.
JCI Insight|June 23, 2025
A TMPRSS6-inhibiting mAb improves disease in a β-thalassemia mouse model and reduces iron in healthy humansHeinrich E Lob, Nikhil Singh, Kusha Mohammadi, et al.
European Journal of Human Genetics : EJHG|May 8, 2020
Functional biology of the Steel syndrome founder allele and evidence for clan genomics derivation of COL27A1 pathogenic alleles worldwideClaudia Gonzaga-Jauregui, Gozde Yesil, Harikiran Nistala, et al.
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