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The Journal of Pain|September 16, 2019
Spinal DN-9, a Peptidic Multifunctional Opioid/Neuropeptide FF Agonist Produced Potent Nontolerance Forming Analgesia With Limited Side EffectsZilong Wang, Biao Xu, Changyu Jiang, et al.
Neuropharmacology|June 17, 2020
VF-13, a chimeric peptide of VD-hemopressin(α) and neuropeptide VF, produces potent antinociception with reduced cannabinoid-related side effectsBiao Xu, Jian Xiao, Kangtai Xu, et al.
Neuropeptides|November 26, 2021
NOP01, a NOP receptor agonist, produced potent and peripherally restricted antinociception in a formalin-induced mouse orofacial pain modelJian Xiao, Jiandong Niu, Biao Xu, et al.
European Journal of Pharmacology|May 2, 2021
Spinal endomorphins attenuate burn-injury pain in male mice by inhibiting p38 MAPK signaling pathway through the mu-opioid receptorTing Zhang, Run Zhang, Biao Xu, et al.
Brain : a Journal of Neurology|February 25, 2026
Distinct contribution of spinal neuropeptide Y and NPY1R neurons to morphine analgesiaYifei Wu, Yiming Chen, Qian Zeng, et al.
European Journal of Pharmacology|May 17, 2020
Spinal administration of the multi-functional opioid/neuropeptide FF agonist BN-9 produced potent antinociception without development of tolerance and opioid-induced hyperalgesiaRun Zhang, Biao Xu, Qinqin Zhang, et al.
ACS Chemical Neuroscience|October 20, 2022
OFP011 Cyclic Peptide as a Multifunctional Agonist for Opioid/Neuropeptide FF Receptors with Improved Blood-Brain Barrier PenetrationMengna Zhang, Biao Xu, Ning Li, et al.
Nature Communications|August 1, 2025
Neuropeptide Y neurons mediate opioid-induced itch by disinhibiting GRP-GRPR microcircuits in the spinal cordQian Zeng, Yitong Li, Yifei Wu, et al.
Anesthesia and Analgesia|January 13, 2023
OCP002, a Mixed Agonist of Opioid and Cannabinoid Receptors, Produces Potent Antinociception With Minimized Side EffectsBiao Xu, Qinqin Zhang, Dan Chen, et al.
Journal of Medicinal Chemistry|December 3, 2020
Synthesis and Biological Characterization of Cyclic Disulfide-Containing Peptide Analogs of the Multifunctional Opioid/Neuropeptide FF Receptor Agonists That Produce Long-Lasting and Nontolerant AntinociceptionMengna Zhang, Biao Xu, Ning Li, et al.
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