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CPT: Pharmacometrics & Systems Pharmacology
|
December 14, 2025
A Generalized Minimal PBPK-PD Model of Bispecific Antibodies: Case Studies and Applications in Drug Development
Phillip Spinosa, Louis Joslyn, Saroja Ramanujan, et al.
Journal of Lipid Research
|
November 3, 2015
Evaluation of HDL-modulating interventions for cardiovascular risk reduction using a systems pharmacology approach
Kapil Gadkar, James Lu, Srikumar Sahasranaman, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
January 21, 2020
gQSPSim: A SimBiology-Based GUI for Standardized QSP Model Development and Application
Iraj Hosseini, Justin Feigelman, Anita Gajjala, et al.
Journal of Pharmacokinetics and Pharmacodynamics
|
January 6, 2018
gPKPDSim: a SimBiology<sup>®</sup>-based GUI application for PKPD modeling in drug development
Iraj Hosseini, Anita Gajjala, Daniela Bumbaca Yadav, et al.
NPJ Systems Biology and Applications
|
August 30, 2020
Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling
Iraj Hosseini, Kapil Gadkar, Eric Stefanich, et al.
Molecular Pharmaceutics
|
June 21, 2017
Ocular Pharmacokinetics of Therapeutic Antibodies Given by Intravitreal Injection: Estimation of Retinal Permeabilities Using a 3-Compartment Semi-Mechanistic Model
Laurence A Hutton-Smith, Eamonn A Gaffney, Helen M Byrne, et al.
Genome Research
|
September 3, 2004
A benchmark for methods in reverse engineering and model discrimination: problem formulation and solutions
Andreas Kremling, Sophia Fischer, Kapil Gadkar, et al.
NPJ Systems Biology and Applications
|
June 27, 2017
Clinical responses to ERK inhibition in <i>BRAF</i><sup>V600E</sup>-mutant colorectal cancer predicted using a computational model
Daniel C Kirouac, Gabriele Schaefer, Jocelyn Chan, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
December 1, 2021
Quantitative systems pharmacology model-based investigation of adverse gastrointestinal events associated with prolonged treatment with PI3-kinase inhibitors
Kapil Gadkar, Christina Friedrich, Vincent Hurez, et al.
NPJ Systems Biology and Applications
|
September 8, 2017
Erratum: Clinical responses to ERK inhibition in <i>BRAF</i><sup>V600E</sup>-mutant colorectal cancer predicted using a computational model
Daniel C Kirouac, Gabriele Schaefer, Jocelyn Chan, et al.
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Search research articles
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Showing results (1-10 of 27) with videos related to
Sort By:
Page
of 3
CPT: Pharmacometrics & Systems Pharmacology
|
December 14, 2025
A Generalized Minimal PBPK-PD Model of Bispecific Antibodies: Case Studies and Applications in Drug Development
Phillip Spinosa, Louis Joslyn, Saroja Ramanujan, et al.
Journal of Lipid Research
|
November 3, 2015
Evaluation of HDL-modulating interventions for cardiovascular risk reduction using a systems pharmacology approach
Kapil Gadkar, James Lu, Srikumar Sahasranaman, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
January 21, 2020
gQSPSim: A SimBiology-Based GUI for Standardized QSP Model Development and Application
Iraj Hosseini, Justin Feigelman, Anita Gajjala, et al.
Journal of Pharmacokinetics and Pharmacodynamics
|
January 6, 2018
gPKPDSim: a SimBiology<sup>®</sup>-based GUI application for PKPD modeling in drug development
Iraj Hosseini, Anita Gajjala, Daniela Bumbaca Yadav, et al.
NPJ Systems Biology and Applications
|
August 30, 2020
Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling
Iraj Hosseini, Kapil Gadkar, Eric Stefanich, et al.
Molecular Pharmaceutics
|
June 21, 2017
Ocular Pharmacokinetics of Therapeutic Antibodies Given by Intravitreal Injection: Estimation of Retinal Permeabilities Using a 3-Compartment Semi-Mechanistic Model
Laurence A Hutton-Smith, Eamonn A Gaffney, Helen M Byrne, et al.
Genome Research
|
September 3, 2004
A benchmark for methods in reverse engineering and model discrimination: problem formulation and solutions
Andreas Kremling, Sophia Fischer, Kapil Gadkar, et al.
NPJ Systems Biology and Applications
|
June 27, 2017
Clinical responses to ERK inhibition in <i>BRAF</i><sup>V600E</sup>-mutant colorectal cancer predicted using a computational model
Daniel C Kirouac, Gabriele Schaefer, Jocelyn Chan, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
December 1, 2021
Quantitative systems pharmacology model-based investigation of adverse gastrointestinal events associated with prolonged treatment with PI3-kinase inhibitors
Kapil Gadkar, Christina Friedrich, Vincent Hurez, et al.
NPJ Systems Biology and Applications
|
September 8, 2017
Erratum: Clinical responses to ERK inhibition in <i>BRAF</i><sup>V600E</sup>-mutant colorectal cancer predicted using a computational model
Daniel C Kirouac, Gabriele Schaefer, Jocelyn Chan, et al.
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of 3