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Cell Death and Differentiation|March 13, 2019
Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreasDritan Liko, Louise Mitchell, Kirsteen J Campbell, et al.Nature Communications|April 12, 2018
Increased formate overflow is a hallmark of oxidative cancerJohannes Meiser, Anne Schuster, Matthias Pietzke, et al.Nature Cell Biology|August 25, 2015
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesisSimone Cardaci, Liang Zheng, Gillian MacKay, et al.Nature Communications|January 24, 2015
Fumarate induces redox-dependent senescence by modifying glutathione metabolismLiang Zheng, Simone Cardaci, Livnat Jerby, et al.Molecular Cancer Therapeutics|February 8, 2022
Dual G9A/EZH2 Inhibition Stimulates Antitumor Immune Response in Ovarian High-Grade Serous CarcinomaPavlina Spiliopoulou, Sarah Spear, Hasan Mirza, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|May 7, 2025
Locking CBL TKBD in its native conformation presents a novel therapeutic opportunity in mutant CBL-dependent leukemiaSyed Feroj Ahmed, Jayanthi Anand, Wei Zhang, et al.The Journal of Investigative Dermatology|March 28, 2015
Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt SignalingJeffrey S Pawlikowski, Claire Brock, Sheau-Chiann Chen, et al.British Journal of Cancer|July 4, 2025
AKT/mTOR as a targetable hub to overcome multimodal resistance to EGFR inhibitors in oesophageal squamous cell carcinomaLindsay C Spender, Dale M Watt, Mark A Baxter, et al.Haematologica|May 18, 2019
Loss of RAF kinase inhibitor protein is involved in myelomonocytic differentiation and aggravates RAS-driven myeloid leukemogenesisVeronica Caraffini, Olivia Geiger, Angelika Rosenberger, et al.Nature Communications|March 13, 2021
An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolismMarisa Nacke, Emma Sandilands, Konstantina Nikolatou, et al.Pageof 15