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Karen L Davis

Showing results (1-10 of 14) with videos related to

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Chemical Research in Toxicology|December 19, 2006
A regulatory perspective on issues and approaches in characterizing human metabolitesKaren L Davis-Bruno, Aisar Atrakchi
Regulatory Toxicology and Pharmacology : RTP|May 13, 2021
Implementation of the principles of the 3Rs of animal testing at CDER: Past, present and futureRonald L Wange, Paul C Brown, Karen L Davis-Bruno
Chemico-Biological Interactions|May 4, 2025
Comparative DNA damage induced by eight nitrosamines in primary human and macaque hepatocytesJi-Eun Seo, Xiaobo He, Matthew Bryant, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|January 3, 2025
Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of four small-molecule nitrosamines with different carcinogenic potencies and tumor target specificitiesXiaoqing Guo, Ji-Eun Seo, Hannah Xu, et al.
Regulatory Toxicology and Pharmacology : RTP|July 10, 2025
Genotoxicity evaluation of ten nitrosamine drug substance-related impurities using 2D and 3D HepaRG cell modelsJi-Eun Seo, Hannah Xu, Xilin Li, et al.
Archives of Toxicology|July 24, 2023
Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell modelsJi-Eun Seo, Joshua Z Yu, Hannah Xu, et al.
Mutagenesis|February 23, 2026
Mutagenicity of N-nitroso-fluoxetine and N-nitroso-varenicline in human HepaRG cell modelsJi-Eun Seo, Hannah Xu, Javier Revollo, et al.
Archives of Toxicology|July 26, 2022
Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450sXilin Li, Xiaobo He, Yuan Le, et al.
Regulatory Toxicology and Pharmacology : RTP|October 21, 2024
Mutagenicity and genotoxicity evaluation of 15 nitrosamine drug substance-related impurities in human TK6 cellsXilin Li, Yuan Le, Xiaoqing Guo, et al.
Toxicology Letters|October 3, 2025
Challenges and solutions in measuring commonly used biomarkers for drug-induced liver injury in a liver-on-a-chip platformQiang Shi, Laura K Schnackenberg, Lijun Ren, et al.
Pageof 2

Showing results (1-10 of 14) with videos related to

Sort By:
Pageof 2
Chemical Research in Toxicology|December 19, 2006
A regulatory perspective on issues and approaches in characterizing human metabolitesKaren L Davis-Bruno, Aisar Atrakchi
Regulatory Toxicology and Pharmacology : RTP|May 13, 2021
Implementation of the principles of the 3Rs of animal testing at CDER: Past, present and futureRonald L Wange, Paul C Brown, Karen L Davis-Bruno
Chemico-Biological Interactions|May 4, 2025
Comparative DNA damage induced by eight nitrosamines in primary human and macaque hepatocytesJi-Eun Seo, Xiaobo He, Matthew Bryant, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|January 3, 2025
Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of four small-molecule nitrosamines with different carcinogenic potencies and tumor target specificitiesXiaoqing Guo, Ji-Eun Seo, Hannah Xu, et al.
Regulatory Toxicology and Pharmacology : RTP|July 10, 2025
Genotoxicity evaluation of ten nitrosamine drug substance-related impurities using 2D and 3D HepaRG cell modelsJi-Eun Seo, Hannah Xu, Xilin Li, et al.
Archives of Toxicology|July 24, 2023
Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell modelsJi-Eun Seo, Joshua Z Yu, Hannah Xu, et al.
Mutagenesis|February 23, 2026
Mutagenicity of N-nitroso-fluoxetine and N-nitroso-varenicline in human HepaRG cell modelsJi-Eun Seo, Hannah Xu, Javier Revollo, et al.
Archives of Toxicology|July 26, 2022
Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450sXilin Li, Xiaobo He, Yuan Le, et al.
Regulatory Toxicology and Pharmacology : RTP|October 21, 2024
Mutagenicity and genotoxicity evaluation of 15 nitrosamine drug substance-related impurities in human TK6 cellsXilin Li, Yuan Le, Xiaoqing Guo, et al.
Toxicology Letters|October 3, 2025
Challenges and solutions in measuring commonly used biomarkers for drug-induced liver injury in a liver-on-a-chip platformQiang Shi, Laura K Schnackenberg, Lijun Ren, et al.
Pageof 2