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Antimicrobial Agents and Chemotherapy|March 29, 2005
Development of a cell-based high-throughput specificity screen using a hepatitis C virus-bovine viral diarrhea virus dual replicon assayDonald R O'Boyle, Peter T Nower, Julie A Lemm, et al.Antiviral Research|September 4, 2010
Ligand-induced changes in hepatitis C virus NS5B polymerase structureKaren Rigat, Yi Wang, Thomas W Hudyma, et al.Antimicrobial Agents and Chemotherapy|June 18, 2014
Comparison of daclatasvir resistance barriers on NS5A from hepatitis C virus genotypes 1 to 6: implications for cross-genotype activityChunfu Wang, Lingling Jia, Donald R O'Boyle, et al.Bioorganic & Medicinal Chemistry Letters|April 22, 2011
The synthesis and evaluation of a novel class of (E)-3-(1-cyclohexyl-1H-pyrazol-3-yl)-2-methylacrylic acid hepatitis C virus polymerase NS5B inhibitorsScott W Martin, Peter Glunz, Brett R Beno, et al.Bioorganic & Medicinal Chemistry Letters|March 29, 2011
Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymeraseRobert G Gentles, Steven Sheriff, Brett R Beno, et al.Nature|November 5, 2015
Resensitizing daclatasvir-resistant hepatitis C variants by allosteric modulation of NS5AJin-Hua Sun, Donald R O'Boyle, Robert A Fridell, et al.ACS Medicinal Chemistry Letters|July 26, 2017
Improving Metabolic Stability with Deuterium: The Discovery of BMT-052, a Pan-genotypic HCV NS5B Polymerase InhibitorKyle Parcella, Kyle Eastman, Kap-Sun Yeung, et al.ACS Medicinal Chemistry Letters|January 8, 2019
Structure-Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B InhibitorsKap-Sun Yeung, Brett R Beno, Kathy Mosure, et al.Medchemcomm|August 16, 2018
The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymeraseKyle J Eastman, Kyle Parcella, Kap-Sun Yeung, et al.Journal of Medicinal Chemistry|April 22, 2017
Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical StudiesKap-Sun Yeung, Brett R Beno, Kyle Parcella, et al.Pageof 2