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Methods in Molecular Biology (Clifton, N.J.)|December 31, 2022
3D Hydrogel Cultures for High-Throughput Drug DiscoveryKaren Sperle, Darrin J Pochan, Sigrid A Langhans
Molecular Therapy. Nucleic Acids|September 10, 2018
Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMSStephanie Tantzer, Karen Sperle, Kaitlin Kenaley, et al.
Annals of Neurology|September 27, 2002
A PLP splicing abnormality is associated with an unusual presentation of PMDGrace M Hobson, Zhong Huang, Karen Sperle, et al.
Journal of Cellular Biochemistry|November 17, 2005
PLP1 alternative splicing in differentiating oligodendrocytes: characterization of an exonic splicing enhancerErming Wang, Zhong Huang, Grace M Hobson, et al.
Human Molecular Genetics|June 4, 2014
PMD patient mutations reveal a long-distance intronic interaction that regulates PLP1/DM20 alternative splicingJennifer R Taube, Karen Sperle, Linda Banser, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|July 19, 2013
Gait abnormalities and progressive myelin degeneration in a new murine model of Pelizaeus-Merzbacher disease with tandem genomic duplicationKristi Clark, Lauren Sakowski, Karen Sperle, et al.
Annals of Neurology|December 24, 2005
Spastic paraplegia type 2 associated with axonal neuropathy and apparent PLP1 position effectJennifer A Lee, Ricardo E Madrid, Karen Sperle, et al.
Human Mutation|November 16, 2005
Splice-site contribution in alternative splicing of PLP1 and DM20: molecular studies in oligodendrocytesGrace M Hobson, Zhong Huang, Karen Sperle, et al.
Experimental Neurology|October 7, 2008
Deletion of a splicing enhancer disrupts PLP1/DM20 ratio and myelin stabilityErming Wang, Neviana Dimova, Karen Sperle, et al.
Annals of Neurology|February 26, 2003
Schwann cell expression of PLP1 but not DM20 is necessary to prevent neuropathyMichael E Shy, Grace Hobson, Manisha Jain, et al.
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