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Biochemical Pharmacology|August 9, 2003
A dual mechanism of action of the anticancer agent F 11782 on human topoisomerase II alphaLars H Jensen, Axelle Renodon-Cornière, Karin C Nitiss, et al.DNA Repair|April 5, 2015
TDP1 promotes assembly of non-homologous end joining protein complexes on DNAJinho Heo, Jing Li, Matthew Summerlin, et al.Proceedings of the National Academy of Sciences of the United States of America|July 5, 2023
Naturally mutagenic sequence diversity in a human type II topoisomeraseAfif F Bandak, Tim R Blower, Karin C Nitiss, et al.Proceedings of the National Academy of Sciences of the United States of America|January 21, 2022
Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancersArnoud Boot, Mo Liu, Nicole Stantial, et al.The Journal of Biological Chemistry|March 24, 2004
A mutation in human topoisomerase II alpha whose expression is lethal in DNA repair-deficient yeast cellsJerrylaine V Walker, Karin C Nitiss, Lars H Jensen, et al.Proceedings of the National Academy of Sciences of the United States of America|October 13, 2020
Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeastNicole Stantial, Anna Rogojina, Matthew Gilbertson, et al.The Journal of Biological Chemistry|May 9, 2014
Proteolytic degradation of topoisomerase II (Top2) enables the processing of Top2·DNA and Top2·RNA covalent complexes by tyrosyl-DNA-phosphodiesterase 2 (TDP2)Rui Gao, Matthew J Schellenberg, Shar-Yin N Huang, et al.Journal of Molecular Biology|August 21, 2007
Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poisonXiaoping He, Robert C A M van Waardenburg, Kerim Babaoglu, et al.Nature Neuroscience|May 6, 2014
Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromesSachin Katyal, Youngsoo Lee, Karin C Nitiss, et al.Atherosclerosis|May 31, 2016
The western-type diet induces anti-HMGB1 autoimmunity in Apoe(-/-) miceYue Pan, Hanzhong Ke, Zhaoqi Yan, et al.Pageof 4