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Journal of the American Chemical Society
|
August 22, 2002
Computational study of the influence of solvent on (16)O/(18)O equilibrium isotope effects in phosphate deprotonation reactions
Karin Kolmodin, Victor B Luzhkov, Johan Aqvist
Journal of Computer-Aided Molecular Design
|
March 14, 2009
Design of compound libraries for fragment screening
Niklas Blomberg, David A Cosgrove, Peter W Kenny, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
April 29, 2004
Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii
Malin Graffner-Nordberg, Karin Kolmodin, Johan Aqvist, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Creation of Novel Cores for β-Secretase (BACE-1) Inhibitors: A Multiparameter Lead Generation Strategy
Jenny Viklund, Karin Kolmodin, Gunnar Nordvall, et al.
Biochemical and Biophysical Research Communications
|
January 26, 2010
Evidence for dimeric BACE-mediated APP processing
Shaobo Jin, Karin Agerman, Karin Kolmodin, et al.
Drug Metabolism Reviews
|
March 17, 2007
State-of-the-art tools for computational site of metabolism predictions: comparative analysis, mechanistical insights, and future applications
Lovisa Afzelius, Catrin Hasselgren Arnby, Anders Broo, et al.
The Journal of Biological Chemistry
|
October 11, 2012
Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease
Fredrik Jeppsson, Susanna Eketjäll, Juliette Janson, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
June 14, 2013
AZ-4217: a high potency BACE inhibitor displaying acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice
Susanna Eketjäll, Juliette Janson, Fredrik Jeppsson, et al.
Journal of Medicinal Chemistry
|
April 5, 2018
Toward β-Secretase-1 Inhibitors with Improved Isoform Selectivity
Patrik Johansson, Karin Kaspersson, Ian K Gurrell, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 14, 2012
Aminoimidazoles as BACE-1 inhibitors: the challenge to achieve in vivo brain efficacy
Britt-Marie Swahn, Jörg Holenz, Jacob Kihlström, et al.
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of 2
Search research articles
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Showing results (1-10 of 14) with videos related to
Sort By:
Page
of 2
Journal of the American Chemical Society
|
August 22, 2002
Computational study of the influence of solvent on (16)O/(18)O equilibrium isotope effects in phosphate deprotonation reactions
Karin Kolmodin, Victor B Luzhkov, Johan Aqvist
Journal of Computer-Aided Molecular Design
|
March 14, 2009
Design of compound libraries for fragment screening
Niklas Blomberg, David A Cosgrove, Peter W Kenny, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
April 29, 2004
Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii
Malin Graffner-Nordberg, Karin Kolmodin, Johan Aqvist, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Creation of Novel Cores for β-Secretase (BACE-1) Inhibitors: A Multiparameter Lead Generation Strategy
Jenny Viklund, Karin Kolmodin, Gunnar Nordvall, et al.
Biochemical and Biophysical Research Communications
|
January 26, 2010
Evidence for dimeric BACE-mediated APP processing
Shaobo Jin, Karin Agerman, Karin Kolmodin, et al.
Drug Metabolism Reviews
|
March 17, 2007
State-of-the-art tools for computational site of metabolism predictions: comparative analysis, mechanistical insights, and future applications
Lovisa Afzelius, Catrin Hasselgren Arnby, Anders Broo, et al.
The Journal of Biological Chemistry
|
October 11, 2012
Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease
Fredrik Jeppsson, Susanna Eketjäll, Juliette Janson, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
June 14, 2013
AZ-4217: a high potency BACE inhibitor displaying acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice
Susanna Eketjäll, Juliette Janson, Fredrik Jeppsson, et al.
Journal of Medicinal Chemistry
|
April 5, 2018
Toward β-Secretase-1 Inhibitors with Improved Isoform Selectivity
Patrik Johansson, Karin Kaspersson, Ian K Gurrell, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 14, 2012
Aminoimidazoles as BACE-1 inhibitors: the challenge to achieve in vivo brain efficacy
Britt-Marie Swahn, Jörg Holenz, Jacob Kihlström, et al.
Page
of 2