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The Journal of Biological Chemistry|October 6, 2019
The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensingTravis B Lear, Karina C Lockwood, Yurong Ouyang, et al.
The FEBS Journal|March 20, 2023
KIAA0317 regulates SOCS1 stability to ameliorate colonic inflammationKarina C Lockwood, Travis B Lear, Shristi Rajbhandari, et al.
The Journal of Biological Chemistry|October 27, 2023
E3 ubiquitin ligase ZBTB25 suppresses beta coronavirus infection through ubiquitination of the main viral protease MProTravis B Lear, Áine N Boudreau, Karina C Lockwood, et al.
JCI Insight|January 29, 2020
The RNFT2/IL-3Rα axis regulates IL-3 signaling and innate immunityYao Tong, Travis B Lear, John Evankovich, et al.
The Journal of Biological Chemistry|February 20, 2020
Kelch-like protein 42 is a profibrotic ubiquitin E3 ligase involved in systemic sclerosisTravis B Lear, Karina C Lockwood, Mads Larsen, et al.
Research Square|August 21, 2020
A high throughput screen for TMPRSS2 expression identifies FDA-approved and clinically advanced compounds that can limit SARS-CoV-2 entryYanwen Chen, Travis B Lear, John W Evankovich, et al.
Nature Communications|June 24, 2021
A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entryYanwen Chen, Travis B Lear, John W Evankovich, et al.
JCI Insight|October 4, 2019
KIAA0317 regulates pulmonary inflammation through SOCS2 degradationTravis B Lear, Alison C McKelvey, John W Evankovich, et al.
Science Advances|June 4, 2025
Inhibition of virally induced TFEB proteasomal degradation as a host-centric therapeutic approach for coronaviral infectionTravis B Lear, Mads B Larsen, Bo Lin, et al.
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