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The Journal of Biological Chemistry|May 31, 2020
Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1Julie A Mund, SuJung Park, Abbi E Smith, et al.
Neuro-Oncology Advances|August 1, 2026
Malignant peripheral nerve sheath tumor development during MEK inhibitor treatment: A pre-clinical study and a clinical case seriesAndrea M Gross, Steven D Rhodes, Anne Dufek, et al.
The Journal of Biological Chemistry|February 18, 2011
p85alpha regulates osteoblast differentiation by cross-talking with the MAPK pathwayXiaohua Wu, Shi Chen, Selina A Orlando, et al.
Blood|March 8, 2003
Functional p85alpha gene is required for normal murine fetal erythropoiesisHannah Huddleston, Bailin Tan, Feng-Chun Yang, et al.
Circulation|December 28, 2013
Neurofibromin-deficient myeloid cells are critical mediators of aneurysm formation in vivoFang Li, Brandon D Downing, Lucy C Smiley, et al.
Human Molecular Genetics|June 2, 2021
PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2)Eric Hawley, Jeffrey Gehlhausen, Sofiia Karchugina, et al.
Journal of Immunology (Baltimore, Md. : 1950)|March 22, 2002
The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytesBen A Croker, David M Tarlinton, Leonie A Cluse, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 10, 2025
Hydroxychloroquine prevents resistance and potentiates the antitumor effect of SHP2 inhibition in NF1-associated malignant peripheral nerve sheath tumorsSameer Farouk Sait, Kwan Ho Tang, Steven P Angus, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi|December 30, 2014
[Anti-mouse CD122 antibody promotes the hematopoietic repopulating capacity of cord blood CD34⁺ cells in NOD/SCID mice]Men-Yao Sheng, Hui Shi, Wen Xing, et al.
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