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RSC Chemical Biology|March 13, 2023
Protein-protein interfaces in molecular glue-induced ternary complexes: classification, characterization, and predictionHuan Rui, Kate S Ashton, Jaeki Min, et al.The Journal of Organic Chemistry|April 1, 2014
Nonracemic synthesis of GK-GKRP disruptor AMG-3969Matthew P Bourbeau, Kate S Ashton, Jie Yan, et al.Organic & Biomolecular Chemistry|January 23, 2004
Synthetic anisomycin analogues activating the JNK/SAPK1 and p38/SAPK2 pathwaysEdward M Rosser, Simon Morton, Kate S Ashton, et al.Bioorganic & Medicinal Chemistry Letters|August 10, 2011
Design and synthesis of novel amide AKT1 inhibitors with selectivity over CDK2Kate S Ashton, David J St Jean, Steve F Poon, et al.Cell Chemical Biology|March 6, 2025
VIPER-TACs leverage viral E3 ligases for disease-specific targeted protein degradationKyle Mangano, Robert G Guenette, Spencer Hill, et al.Journal of Medicinal Chemistry|July 9, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 4. Exploration of a novel binding pocketFang-Tsao Hong, Mark H Norman, Kate S Ashton, et al.Journal of Medicinal Chemistry|March 12, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine seriesNobuko Nishimura, Mark H Norman, Longbin Liu, et al.Nature Communications|August 21, 2025
LYMTACs:chimeric small molecules repurpose lysosomal membrane proteins for target protein relocalization and degradationDhanusha A Nalawansha, Georgios Mazis, Gitte Husemoen, et al.Journal of Medicinal Chemistry|March 14, 2022
Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical ProbeNuria A Tamayo, Matthew P Bourbeau, Jennifer R Allen, et al.Journal of Medicinal Chemistry|January 11, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-conceptKate S Ashton, Kristin L Andrews, Marian C Bryan, et al.Pageof 2