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Current Drug Metabolism|January 24, 2018
Current State of In vitro Cell-Based Renal ModelsElnaz Gozalpour, Katherine S Fenner
ALTEX|November 7, 2022
Amplifying the impact of kidney microphysiological systems: predicting renal drug clearance using mechanistic modelling based on reconstructed drug secretionPedro Caetano-Pinto, Pär Nordell, Tom Nieskens, et al.
Biochemical Pharmacology|November 9, 2011
Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenumTheodora G H A Tucker, Alison M Milne, Sylvie Fournel-Gigleux, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|November 15, 2011
The evolution of the OATP hepatic uptake transport protein family in DMPK sciences: from obscure liver transporters to key determinants of hepatobiliary clearanceKatherine S Fenner, Hannah M Jones, Mohammed Ullah, et al.
Journal of Pharmaceutical Sciences|April 18, 2009
N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine (CP-100,356) as a "chemical knock-out equivalent" to assess the impact of efflux transporters on oral drug absorption in the ratAmit S Kalgutkar, Kosea S Frederick, Jonathan Chupka, et al.
Current Drug Metabolism|December 30, 2010
Targeting intestinal transporters for optimizing oral drug absorptionManthena V Varma, Catherine M Ambler, Mohammad Ullah, et al.
British Journal of Clinical Pharmacology|March 12, 2011
A comprehensive non-clinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladderErnesto Callegari, Bimal Malhotra, Peter J Bungay, et al.
Molecular Pharmaceutics|December 23, 2009
Refining the in vitro and in vivo critical parameters for P-glycoprotein, [I]/IC50 and [I2]/IC50, that allow for the exclusion of drug candidates from clinical digoxin interaction studiesJack A Cook, Bo Feng, Katherine S Fenner, et al.
Molecular Pharmacology|May 4, 2018
Molecular Mechanisms for Species Differences in Organic Anion Transporter 1, OAT1: Implications for Renal Drug ToxicityLing Zou, Adrian Stecula, Anshul Gupta, et al.
Molecular Pharmaceutics|April 12, 2012
pH-Dependent solubility and permeability criteria for provisional biopharmaceutics classification (BCS and BDDCS) in early drug discoveryManthena V Varma, Iain Gardner, Stefanus J Steyn, et al.
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