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Molecular Therapy. Advances|May 15, 2026
Optimized AAV vector enables potent therapeutic rescue of inherited glycosylphosphatidylinositol deficiency in miceSaori Umeshita, Kae Imanishi, Shibi Likhite, et al.Molecular Therapy. Methods & Clinical Development|January 16, 2024
AAV-based gene therapy ameliorated CNS-specific GPI defect in mouse modelsYoshiko Murakami, Saori Umeshita, Kae Imanishi, et al.Molecular Therapy. Methods & Clinical Development|July 18, 2024
The postnatal injection of AAV9-FOXG1 rescues corpus callosum agenesis and other brain deficits in the mouse model of FOXG1 syndromeShin Jeon, Jaein Park, Shibi Likhite, et al.Molecular Therapy. Methods & Clinical Development|September 25, 2023
In-depth comparison of Anc80L65 and AAV9 retinal targeting and characterization of cross-reactivity to multiple AAV serotypes in humansMaura K Schwartz, Shibi Likhite, Tatyana A Vetter, et al.Iscience|August 29, 2022
EphA4 targeting agents protect motor neurons from cell death induced by amyotrophic lateral sclerosis -astrocytesCassandra Dennys, Carlo Baggio, Rochelle Rodrigo, et al.International Journal of Molecular Sciences|March 29, 2023
Prevalence of Neutralizing Antibodies against Adeno-Associated Virus Serotypes 1, 2, and 9 in Non-Injected Latin American Patients with Heart Failure-ANVIAS StudyJulieth A Sierra-Delgado, Shibi Likhite, Paula K Bautista, et al.Neurobiology of Aging|May 8, 2021
Follistatin-induced muscle hypertrophy in aged mice improves neuromuscular junction innervation and functionChitra C Iyer, Deepti Chugh, Prameela J Bobbili, et al.Cell Reports|February 18, 2024
RNA helicase IGHMBP2 regulates THO complex to ensure cellular mRNA homeostasisArchana Bairavasundaram Prusty, Anja Hirmer, Julieth Andrea Sierra-Delgado, et al.Journal of Biomedical Science|January 4, 2026
AAV9 gene therapy optimization for SMARD1/CMT2S: safety and long-term efficacy comparison of two vectors in a SMARD1 preclinical modelElisa Pagliari, Alessia Anastasia, Floriana Bellandi, et al.Molecular Therapy. Methods & Clinical Development|September 11, 2024
Combination AAV therapy with galectin-1 and SOD1 downregulation demonstrates superior therapeutic effect in a severe ALS mouse modelMegan C Baird, Shibi B Likhite, Tatyana A Vetter, et al.Pageof 2