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Katie T Freeman

Showing results (11-20 of 36) with videos related to

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Molecules (Basel, Switzerland)|April 25, 2019
Structure⁻Activity Relationships of the Tetrapeptide Ac-His-Arg-(<i>p</i>I)DPhe-Tic-NH<sub>2</sub> at the Mouse Melanocortin Receptors: Modification at the (<i>p</i>I)DPhe Position Leads to mMC3R Versus mMC4R Selective LigandsKatherine N Schlasner, Mark D Ericson, Skye R Doering, et al.
Journal of Medicinal Chemistry|April 19, 2018
Developing a Biased Unmatched Bivalent Ligand (BUmBL) Design Strategy to Target the GPCR Homodimer Allosteric Signaling (cAMP over β-Arrestin 2 Recruitment) Within the Melanocortin ReceptorsCody J Lensing, Katie T Freeman, Sathya M Schnell, et al.
Journal of Medicinal Chemistry|March 10, 2016
An in Vitro and in Vivo Investigation of Bivalent Ligands That Display Preferential Binding and Functional Activity for Different Melanocortin Receptor HomodimersCody J Lensing, Katie T Freeman, Sathya M Schnell, et al.
ACS Chemical Neuroscience|December 20, 2017
1,2,3-Triazole Rings as a Disulfide Bond Mimetic in Chimeric AGRP-Melanocortin Peptides: Design, Synthesis, and Functional CharacterizationSrinivasa R Tala, Anamika Singh, Cody J Lensing, et al.
Journal of Medicinal Chemistry|December 18, 2019
Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-dPro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor AntagonistsZoe M Koerperich, Mark D Ericson, Katie T Freeman, et al.
ACS Chemical Neuroscience|January 25, 2018
Structure-Activity Relationship Studies of a Macrocyclic AGRP-Mimetic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-DPro] Yield Potent and Selective Melanocortin-4 Receptor Antagonists and Melanocortin-5 Receptor Inverse Agonists That Increase Food Intake in MiceKatlyn A Fleming, Mark D Ericson, Katie T Freeman, et al.
Neurobiology of Aging|October 16, 2010
The effect of aging on the density of the sensory nerve fiber innervation of bone and acute skeletal painJuan M Jimenez-Andrade, William G Mantyh, Aaron P Bloom, et al.
Molecular Pain|December 9, 2010
Administration of a tropomyosin receptor kinase inhibitor attenuates sarcoma-induced nerve sprouting, neuroma formation and bone cancer painJoseph R Ghilardi, Katie T Freeman, Juan M Jimenez-Andrade, et al.
ACS Pharmacology & Translational Science|April 18, 2024
Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]Mark D Ericson, Katie T Freeman, Courtney M Larson, et al.
ACS Chemical Neuroscience|January 28, 2017
A Direct in Vivo Comparison of the Melanocortin Monovalent Agonist Ac-His-DPhe-Arg-Trp-NH<sub>2</sub> versus the Bivalent Agonist Ac-His-DPhe-Arg-Trp-PEDG20-His-DPhe-Arg-Trp-NH<sub>2</sub>: A Bivalent AdvantageCody J Lensing, Danielle N Adank, Stacey L Wilber, et al.
Pageof 4

Showing results (11-20 of 36) with videos related to

Sort By:
Pageof 4
Molecules (Basel, Switzerland)|April 25, 2019
Structure⁻Activity Relationships of the Tetrapeptide Ac-His-Arg-(<i>p</i>I)DPhe-Tic-NH<sub>2</sub> at the Mouse Melanocortin Receptors: Modification at the (<i>p</i>I)DPhe Position Leads to mMC3R Versus mMC4R Selective LigandsKatherine N Schlasner, Mark D Ericson, Skye R Doering, et al.
Journal of Medicinal Chemistry|April 19, 2018
Developing a Biased Unmatched Bivalent Ligand (BUmBL) Design Strategy to Target the GPCR Homodimer Allosteric Signaling (cAMP over β-Arrestin 2 Recruitment) Within the Melanocortin ReceptorsCody J Lensing, Katie T Freeman, Sathya M Schnell, et al.
Journal of Medicinal Chemistry|March 10, 2016
An in Vitro and in Vivo Investigation of Bivalent Ligands That Display Preferential Binding and Functional Activity for Different Melanocortin Receptor HomodimersCody J Lensing, Katie T Freeman, Sathya M Schnell, et al.
ACS Chemical Neuroscience|December 20, 2017
1,2,3-Triazole Rings as a Disulfide Bond Mimetic in Chimeric AGRP-Melanocortin Peptides: Design, Synthesis, and Functional CharacterizationSrinivasa R Tala, Anamika Singh, Cody J Lensing, et al.
Journal of Medicinal Chemistry|December 18, 2019
Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-dPro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor AntagonistsZoe M Koerperich, Mark D Ericson, Katie T Freeman, et al.
ACS Chemical Neuroscience|January 25, 2018
Structure-Activity Relationship Studies of a Macrocyclic AGRP-Mimetic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-DPro] Yield Potent and Selective Melanocortin-4 Receptor Antagonists and Melanocortin-5 Receptor Inverse Agonists That Increase Food Intake in MiceKatlyn A Fleming, Mark D Ericson, Katie T Freeman, et al.
Neurobiology of Aging|October 16, 2010
The effect of aging on the density of the sensory nerve fiber innervation of bone and acute skeletal painJuan M Jimenez-Andrade, William G Mantyh, Aaron P Bloom, et al.
Molecular Pain|December 9, 2010
Administration of a tropomyosin receptor kinase inhibitor attenuates sarcoma-induced nerve sprouting, neuroma formation and bone cancer painJoseph R Ghilardi, Katie T Freeman, Juan M Jimenez-Andrade, et al.
ACS Pharmacology & Translational Science|April 18, 2024
Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]Mark D Ericson, Katie T Freeman, Courtney M Larson, et al.
ACS Chemical Neuroscience|January 28, 2017
A Direct in Vivo Comparison of the Melanocortin Monovalent Agonist Ac-His-DPhe-Arg-Trp-NH<sub>2</sub> versus the Bivalent Agonist Ac-His-DPhe-Arg-Trp-PEDG20-His-DPhe-Arg-Trp-NH<sub>2</sub>: A Bivalent AdvantageCody J Lensing, Danielle N Adank, Stacey L Wilber, et al.
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