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Nature|June 14, 2017
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistanceSydney M Shaffer, Margaret C Dunagin, Stefan R Torborg, et al.
Cell Reports|May 24, 2016
Oncogenic BRAF-Mediated Melanoma Cell InvasionHezhe Lu, Shujing Liu, Gao Zhang, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 18, 2015
Personalized Preclinical Trials in BRAF Inhibitor-Resistant Patient-Derived Xenograft Models Identify Second-Line Combination TherapiesClemens Krepler, Min Xiao, Katrin Sproesser, et al.
Molecular Cancer Therapeutics|March 3, 2026
JNJ-79032421, a Novel Membrane-restricted Mesothelin-targeting T-cell-engaging Bispecific Antibody for the Treatment of Mesothelin-positive CancersKarine Smans, Thomas Nesspor, Sabine De Breucker, et al.
Cell Reports|December 7, 2017
Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary ConvergenceKatherine R Singleton, Lorin Crawford, Elizabeth Tsui, et al.
Cell Reports|September 24, 2013
Concurrent MEK2 mutation and BRAF amplification confer resistance to BRAF and MEK inhibitors in melanomaJessie Villanueva, Jeffrey R Infante, Clemens Krepler, et al.
Cell Reports|November 16, 2017
Genetic and Genomic Characterization of 462 Melanoma Patient-Derived Xenografts, Tumor Biopsies, and Cell LinesBradley Garman, Ioannis N Anastopoulos, Clemens Krepler, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 22, 2008
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activityJames Tsai, John T Lee, Weiru Wang, et al.
Nature|September 28, 2017
PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomasHezhe Lu, Shujing Liu, Gao Zhang, et al.
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