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ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of a Highly Potent and Selective MEK Inhibitor: GSK1120212 (JTP-74057 DMSO Solvate)Hiroyuki Abe, Shinichi Kikuchi, Kazuhide Hayakawa, et al.
ACS Medicinal Chemistry Letters|January 29, 2016
SAR Exploration Guided by LE and Fsp(3): Discovery of a Selective and Orally Efficacious RORγ InhibitorKazuyuki Hirata, Masayuki Kotoku, Noriyoshi Seki, et al.
Journal of Medicinal Chemistry|July 18, 2025
A Concise and Modular Approach to Generate Novel RORγ AgonistsShunichi Fukuda, Taku Ikenogami, Kazuki Otake, et al.
Journal of Medicinal Chemistry|January 3, 2024
Discovery and SAR of JTE-151: A Novel RORγ Inhibitor for Clinical DevelopmentTakaki Maeba, Kazuyuki Hirata, Masayuki Kotoku, et al.
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