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The AAPS Journal|January 14, 2022
In Vitro to In Vivo Extrapolation Linked to Physiologically Based Pharmacokinetic Models for Assessing the Brain Drug DispositionYukiko Murata, Sibylle Neuhoff, Amin Rostami-Hodjegan, et al.European Journal of Clinical Pharmacology|March 9, 2007
Linking preclinical and clinical whole-body physiologically based pharmacokinetic models with prior distributions in NONMEMGrant Langdon, Ivelina Gueorguieva, Leon Aarons, et al.Toxicological Sciences : an Official Journal of the Society of Toxicology|December 19, 2015
Designing More Efficient Preclinical Experiments: A Simulation Study in Chemotherapy-Induced MyelosupressionEmma C Martin, Leon Aarons, James W T YatesJournal of Clinical Pharmacology|June 16, 2017
Population Pharmacokinetics of Imatinib in Nigerians With Chronic Myeloid Leukemia: Clinical Implications for Dosing and ResistanceBabatunde Ayodeji Adeagbo, Tiwalade Adewale Olugbade, Muheez Alani Durosinmi, et al.Therapeutic Drug Monitoring|January 28, 2003
A Bayesian method based on clotting factor activity for the prediction of maintenance warfarin dosage regimensMaria Pitsiu, Eva M Parker, Leon Aarons, et al.Cancer Chemotherapy and Pharmacology|May 26, 2016
Accounting for dropout in xenografted tumour efficacy studies: integrated endpoint analysis, reduced bias and better use of animalsEmma C Martin, Leon Aarons, James W T YatesJournal of Pharmacokinetics and Pharmacodynamics|December 16, 2018
Variance based global sensitivity analysis of physiologically based pharmacokinetic absorption models for BCS I-IV drugsNicola Melillo, Leon Aarons, Paolo Magni, et al.Cancer Chemotherapy and Pharmacology|July 29, 2018
Pharmacodynamic modelling of resistance to epidermal growth factor receptor inhibition in brain metastasis mouse modelsEmma C Martin, Leon Aarons, James W T YatesPharmaceutical Research|September 24, 2005
Uncertainty analysis in pharmacokinetics and pharmacodynamics: application to naratriptanIvelina Gueorguieva, Ivan A Nestorov, Leon Aarons, et al.Annals of the Rheumatic Diseases|June 7, 2019
Development and validation of a methotrexate adherence assayJames Bluett, Isabel Riba-Garcia, Suzanne M M Verstappen, et al.Pageof 17