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European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|March 5, 2021
Investigating the impact of target lesion selection on drug effect evaluation and tumour growth rate determination using tumour growth inhibition models: Example of malignant pleural mesothelioma patients treated with cisplatin alone or in combination with pemetrexedAurélie Lombard, Hitesh Mistry, Sonya C Chapman, et al.Journal of Clinical Pharmacology|October 15, 2013
Precision criteria to derive sample size when designing pediatric pharmacokinetic studies: which measure of variability should be used?Farzaneh Salem, Kayode Ogungbenro, Pavan Vajjah, et al.European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|April 19, 2024
Hierarchical cluster analysis and nonlinear mixed-effects modelling for candidate biomarker detection in preclinical models of cancerDavid Hodson, Hitesh Mistry, James Yates, et al.The AAPS Journal|February 5, 2020
Global Sensitivity Analysis of the Rodgers and Rowland Model for Prediction of Tissue: Plasma Partitioning Coefficients: Assessment of the Key Physiological and Physicochemical Factors That Determine Small-Molecule Tissue DistributionEstelle Yau, Andrés Olivares-Morales, Michael Gertz, et al.Paediatric Anaesthesia|November 18, 2018
A study of the dosage and duration for levobupivacaine infusion by the caudal-epidural route in infants aged 3-6 monthsRita Vashisht, Anju A Bendon, Ijeoma Okonkwo, et al.Clinical Pharmacology and Therapeutics|August 4, 2021
Model-Based Drug-Drug Interaction Extrapolation Strategy From Adults to Children: Risdiplam in Pediatric Patients With Spinal Muscular AtrophyYumi Cleary, Michael Gertz, Paul Grimsey, et al.The Journal of Pharmacology and Experimental Therapeutics|June 22, 2023
Radiation in Combination with Immune Checkpoint Blockade and DNA Damage Response Inhibitors in Mice: Dosage Optimization in MC38 Syngeneic Tumors via Modelling and SimulationDavid Hodson, Hitesh Mistry, James Yates, et al.CPT: Pharmacometrics & Systems Pharmacology|September 18, 2023
Mixed effects modeling of radiotherapy in combination with immune checkpoint blockade or inhibitors of the DNA damage response pathwayDavid Hodson, Hitesh Mistry, Sofia Guzzetti, et al.Clinical Pharmacokinetics|May 6, 2023
Estimation of FMO3 Ontogeny by Mechanistic Population Pharmacokinetic Modelling of Risdiplam and Its Impact on Drug-Drug Interactions in ChildrenYumi Cleary, Heidemarie Kletzl, Paul Grimsey, et al.Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism|July 15, 2010
Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging studyJames Galea, Kayode Ogungbenro, Sharon Hulme, et al.Pageof 17