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Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 2, 2012
Effect of coadministration of single and multiple doses of rifampicin on the pharmacokinetics of fexofenadine enantiomers in healthy subjectsHiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, et al.Chemical & Pharmaceutical Bulletin|April 21, 2024
In Vitro and in Vivo Study of a Photostable Quinone Compound with Enhanced Therapeutic Efficacy against Chagas DiseaseYutaka Suto, Nagisa Inoue, Mohammed Suliman Omer Tagod, et al.Chemmedchem|September 3, 2025
Development of Keap1-Nrf2 Protein-Protein Interaction Inhibitor Activating Intracellular Nrf2 Based on the Naphthalene-2-acetamide Scaffold, and its Anti-Inflammatory EffectsDaisuke Yasuda, Kai Toyoshima, Koujin Kojima, et al.Chemical Communications (Cambridge, England)|August 8, 2024
An N-ortho-nitrobenzylated benzanilide amino acid enables control of the conformation and membrane permeability of cyclic peptidesYuko Otani, Asami Ichinose, Xihong Wang, et al.Journal of Medicinal Chemistry|December 6, 2022
Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin AmyloidogenesisMineyuki Mizuguchi, Yusuke Nakagawa, Kishin Inui, et al.ACS Medicinal Chemistry Letters|March 18, 2022
Conversion of a PROTAC Mutant Huntingtin Degrader into Small-Molecule Hydrophobic Tags Focusing on Drug-like PropertiesKeigo Hirai, Hiroko Yamashita, Shusuke Tomoshige, et al.Journal of Medicinal Chemistry|April 26, 2024
Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human PlasmaMineyuki Mizuguchi, Yusuke Nakagawa, Takeshi Yokoyama, et al.Biorxiv : the Preprint Server for Biology|July 11, 2025
Structure-guided design and development of cyclic peptide allosteric activators of Polycomb Repressive Complex 2Yasuaki Tokodai, Mark Matyas, Azumi Ishigamori, et al.Nature Communications|March 18, 2023
Amide-to-ester substitution as a stable alternative to N-methylation for increasing membrane permeability in cyclic peptidesYuki Hosono, Satoshi Uchida, Moe Shinkai, et al.Molecular Therapy. Nucleic Acids|April 10, 2025
Correcting tau isoform ratios with a long-acting antisense oligonucleotide alleviates 4R-tauopathy phenotypesKuniyuki Iwata-Endo, Kentaro Sahashi, Kaori Kawai, et al.Pageof 3