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Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan|March 3, 2020
[Evaluation of the Oral Absorption of Ester-type Prodrugs]Kayoko Ohura
Current Drug Metabolism|December 30, 2010
The role of intestinal carboxylesterase in the oral absorption of prodrugsTeruko Imai, Kayoko Ohura
Biological & Pharmaceutical Bulletin|October 2, 2022
Esterases Involved in the Rapid Bioconversion of Esmolol after Intravenous Injection in HumansTeruko Imai, Mizuki Isozaki, Kayoko Ohura
Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan|May 8, 2019
[Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog]Teruko Imai, Yuichiro Nakada, Kayoko Ohura
Journal of Pharmaceutical Sciences|April 5, 2023
Bioconversion and P-gp-Mediated Transport of Depot Fluphenazine Prodrugs after Intramuscular InjectionKayoko Ohura, Yuichiro Nakada, Teruko Imai
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|January 1, 2018
A novel quantification method for serine hydrolases in cellular expression system using fluorophosphonate-biotin probeAmira Abdel-Daim, Kayoko Ohura, Teruko Imai
Journal of Pharmaceutical Sciences|May 9, 2015
Design of Fexofenadine Prodrugs Based on Tissue-Specific Esterase Activity and Their Dissimilar Recognition by P-GlycoproteinKayoko Ohura, Yuichiro Nakada, Shunsuke Kotani, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 26, 2013
Distinct patterns of aging effects on the expression and activity of carboxylesterases in rat liver and intestineKayoko Ohura, Katsumi Tasaka, Mitsuru Hashimoto, et al.
Journal of Pharmaceutical Sciences|April 8, 2019
Identification of Major Esterase Involved in Hydrolysis of Soft Anticholinergic (2R3'R-SGM) Designed From Glycopyrrolate in Human and Rat TissuesAhmed Samir, Kayoko Ohura, Nicholas Bodor, et al.
Journal of Pharmaceutical Sciences|May 28, 2011
Evaluation of transport mechanism of prodrugs and parent drugs formed by intracellular metabolism in Caco-2 cells with modified carboxylesterase activity: temocapril as a model caseKayoko Ohura, Takaaki Nozawa, Koichi Murakami, et al.
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