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Human Molecular Genetics|September 19, 2014
Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brainKazuhiko Tagawa, Hidenori Homma, Ayumu Saito, et al.
Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine|December 8, 2017
The Relationship between Neurite Density Measured with Confocal Microscopy in a Cleared Mouse Brain and Metrics Obtained from Diffusion Tensor and Diffusion Kurtosis ImagingRyusuke Irie, Koji Kamagata, Aurelien Kerever, et al.
Scientific Reports|August 26, 2016
HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's diseaseKyota Fujita, Kazumi Motoki, Kazuhiko Tagawa, et al.
The Journal of Cell Biology|May 5, 2010
Mutant huntingtin impairs Ku70-mediated DNA repairYasushi Enokido, Takuya Tamura, Hikaru Ito, et al.
Scientific Reports|September 23, 2016
Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical librariesTomomi Imamura, Kyota Fujita, Kazuhiko Tagawa, et al.
The Journal of Cell Biology|February 8, 2006
Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73Masataka Hoshino, Mei-ling Qi, Natsue Yoshimura, et al.
Communications Biology|October 12, 2021
HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer's disease pathologyHikari Tanaka, Kanoh Kondo, Kyota Fujita, et al.
Nature Communications|May 9, 2013
A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseasesKyota Fujita, Yoko Nakamura, Tsutomu Oka, et al.
Life Science Alliance|June 16, 2021
DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosisHidenori Homma, Hikari Tanaka, Meihua Jin, et al.
Nature Communications|January 26, 2020
YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathologyHikari Tanaka, Hidenori Homma, Kyota Fujita, et al.
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