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International Journal of Hematology|October 24, 2022
Dual inhibition of EZH1/2 induces cell cycle arrest of B cell acute lymphoblastic leukemia cells through upregulation of CDKN1C and TP53INP1Jumpei Ito, Kazutsune Yamagata, Haruka Shinohara, et al.
Blood|January 27, 2018
Ring1A and Ring1B inhibit expression of Glis2 to maintain murine <i>MOZ-TIF2</i> AML stem cellsHaruko Shima, Emi Takamatsu-Ichihara, Mika Shino, et al.
Molecular Therapy Oncolytics|October 10, 2022
Dual targeting of EZH1 and EZH2 for the treatment of malignant rhabdoid tumorsHaruka Shinohara, Rie Sawado, Makoto Nakagawa, et al.
Leukemia|July 25, 2023
Genetic and chemical targeting of the ATPase complex TIP48 and 49 impairs acute myeloid leukemiaAyuna Hattori, Emi Takamatsu-Ichihara, Yoshiki Yamamoto, et al.
Cancer Science|December 23, 2014
Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cellsYukiko Aikawa, Kazutsune Yamagata, Takuo Katsumoto, et al.
Scientific Reports|September 22, 2017
Mllt10 knockout mouse model reveals critical role of Af10-dependent H3K79 methylation in midfacial developmentHonami Ogoh, Kazutsune Yamagata, Tomomi Nakao, et al.
Cancer Science|April 1, 2021
CDKN1C-mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinibYuki Kagiyama, Shuhei Fujita, Yutaka Shima, et al.
Molecular and Cellular Biology|July 12, 2017
EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in MiceYixin Dong, Kyo-Ichi Isono, Kazuyuki Ohbo, et al.
Cancer Science|October 22, 2018
Dual inhibition of enhancer of zeste homolog 1/2 overactivates WNT signaling to deplete cancer stem cells in multiple myelomaMakoto Nakagawa, Shuhei Fujita, Takuo Katsumoto, et al.
Molecular Cancer Therapeutics|November 16, 2019
A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft ModelYukino Machida, Makoto Nakagawa, Hironori Matsunaga, et al.
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