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Cancer Discovery|October 5, 2022
A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal StabilityKeelan Z Guiley, Kevan M ShokatNature Chemical Biology|July 21, 2022
Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S)Ziyang Zhang, Keelan Z Guiley, Kevan M ShokatNucleic Acids Research|December 23, 2011
Single-pot enzymatic synthesis of Dicer-substrate siRNAsKeelan Z Guiley, Ashley J Pratt, Ian J MacRaeNature Chemical Biology|March 5, 2024
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12DQinheng Zheng, Ziyang Zhang, Keelan Z Guiley, et al.Journal of the American Chemical Society|August 24, 2022
Chemoselective Covalent Modification of K-Ras(G12R) with a Small Molecule ElectrophileZiyang Zhang, Johannes Morstein, Andrew K Ecker, et al.The Journal of Biological Chemistry|August 4, 2022
Cyclin-dependent kinase-mediated phosphorylation and the negative regulatory domain of transcription factor B-Myb modulate its DNA bindingTilini U Wijeratne, Keelan Z Guiley, Hsiau-Wei Lee, et al.Genes & Development|April 29, 2015
Structural mechanisms of DREAM complex assembly and regulationKeelan Z Guiley, Tyler J Liban, Jessica G Felthousen, et al.Nature Structural & Molecular Biology|March 20, 2012
The molecular architecture of human DicerPick-Wei Lau, Keelan Z Guiley, Nabanita De, et al.Proceedings of the National Academy of Sciences of the United States of America|September 19, 2018
Structural mechanism of Myb-MuvB assemblyKeelan Z Guiley, Audra N Iness, Siddharth Saini, et al.Oncogene|September 13, 2018
The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-MybAudra N Iness, Jessica Felthousen, Varsha Ananthapadmanabhan, et al.Pageof 2