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Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 9, 2018
6-Chloro-5-[4-(1-Hydroxycyclobutyl)Phenyl]-1<i>H</i>-Indole-3-Carboxylic Acid is a Highly Selective Substrate for Glucuronidation by UGT1A1, Relative to <i>β</i>-EstradiolKimberly Lapham, Jian Lin, Jonathan Novak, et al.
Journal of the American Chemical Society|August 14, 2015
Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands: Implications for Intracellular ImagingHeather E Murrey, Joshua C Judkins, Christopher W Am Ende, et al.
European Journal of Medicinal Chemistry|November 17, 2019
Structural attributes influencing unbound tissue distributionChristine C Orozco, Karen Atkinson, Sangwoo Ryu, et al.
Bioorganic & Medicinal Chemistry Letters|December 4, 2012
Inhibitors of HIV-1 attachment. Part 9: an assessment of oral prodrug approaches to improve the plasma exposure of a tetrazole-containing derivativeKap-Sun Yeung, Zhilei Qiu, Zheng Yang, et al.
Pharmacology Research & Perspectives|October 19, 2019
Quantitative systems toxicology (QST) reproduces species differences in PF-04895162 liver safety due to combined mitochondrial and bile acid toxicityGrant Generaux, Vinal V Lakhani, Yuching Yang, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 2, 2022
<b>Transporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, A First-in-class Ketohexokinase Inhibitor for Metabolic Disorders and Non-alcoholic Fatty Liver Disease</b>Yan Weng, Kari R Fonseca, Yi-An Bi, et al.
Bioorganic & Medicinal Chemistry Letters|December 4, 2012
Inhibitors of HIV-1 attachment. Part 7: indole-7-carboxamides as potent and orally bioavailable antiviral agentsKap-Sun Yeung, Zhilei Qiu, Quifen Xue, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|September 14, 2020
Mechanistic insights on clearance and inhibition discordance between liver microsomes and hepatocytes when clearance in liver microsomes is higher than in hepatocytesChristopher Keefer, George Chang, Anthony Carlo, et al.
Bioorganic & Medicinal Chemistry Letters|December 4, 2012
Inhibitors of HIV-1 attachment. Part 8: the effect of C7-heteroaryl substitution on the potency, and in vitro and in vivo profiles of indole-based inhibitorsKap-Sun Yeung, Zhilei Qiu, Zhiwei Yin, et al.
Scientific Reports|December 2, 2015
Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)Kim Huard, Janice Brown, Jessica C Jones, et al.
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