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Toxicological Sciences : an Official Journal of the Society of Toxicology|June 13, 2009
Vulnerability to (+)-methamphetamine effects and the relationship to drug disposition in pregnant rats during chronic infusionSarah J White, Elizabeth M Laurenzana, William Brooks Gentry, et al.
Investigative Ophthalmology & Visual Science|February 8, 2018
Nrf2 Activation Is a Potential Therapeutic Approach to Attenuate Diabetic RetinopathyDevy Deliyanti, Saeed F Alrashdi, Sih Min Tan, et al.
Clinical Science (London, England : 1979)|March 24, 2016
A potent Nrf2 activator, dh404, bolsters antioxidant capacity in glial cells and attenuates ischaemic retinopathyDevy Deliyanti, Jae Young Lee, Steven Petratos, et al.
BMC Dermatology|July 15, 2015
Topical application of RTA 408 lotion activates Nrf2 in human skin and is well-tolerated by healthy human volunteersScott A Reisman, Angela R Goldsberry, Chun-Yue I Lee, et al.
American Journal of Physiology. Renal Physiology|April 19, 2013
Bardoxolone methyl analogs RTA 405 and dh404 are well tolerated and exhibit efficacy in rodent models of Type 2 diabetes and obesityMelanie Chin, Chun-Yue Ivy Lee, Jen-Chieh Chuang, et al.
Biochemical and Biophysical Research Communications|February 4, 2014
Dihydro-CDDO-trifluoroethyl amide suppresses inflammatory responses in macrophages via activation of Nrf2Bin Li, Akram Abdalrahman, Yimu Lai, et al.
Biopharmaceutics & Drug Disposition|November 5, 2002
Pharmacokinetics of SB-247083, a potent and selective endothelin(A) receptor antagonist, in the rat, dog, and monkeyKeith W Ward, Leonard M Azzarano, Jayme A Morgan, et al.
Diabetes|April 18, 2014
Derivative of bardoxolone methyl, dh404, in an inverse dose-dependent manner lessens diabetes-associated atherosclerosis and improves diabetic kidney diseaseSih Min Tan, Arpeeta Sharma, Nada Stefanovic, et al.
Biopharmaceutics & Drug Disposition|January 8, 2003
Enhancement of in vitro and in vivo microdialysis recovery of SB-265123 using Intralipid and Encapsin as perfusatesKeith W Ward, Sarah J Medina, Samm T Portelli, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 28, 2004
Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkeyKeith W Ward, Gary J Stelman, Jayme A Morgan, et al.
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