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Handbook of Experimental Pharmacology|December 19, 2009
Approaches for minimizing metabolic activation of new drug candidates in drug discoverySanjeev Kumar, Kaushik Mitra, Kelem Kassahun, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|June 22, 2023
Determination of enzymatic kinetics of metabolism of dimethoate and omethoate in rats and humansGopinath Nallani, Appavu Chandrasekaran, Kelem Kassahun, et al.Toxicology in Vitro : an International Journal Published in Association with BIBRA|May 19, 2025
In vitro metabolic clearance of malathion in rats and humansGopinath Nallani, Appavu Chandrasekaran, Kelem Kassahun, et al.Current Opinion in Drug Discovery & Development|January 5, 2008
Minimizing metabolic activation during pharmaceutical lead optimization: progress, knowledge gaps and future directionsSanjeev Kumar, Kelem Kassahun, Richard A Tschirret-Guth, et al.Toxicology and Applied Pharmacology|November 18, 2017
Age dependent in vitro metabolism of bifenthrin in rat and human hepatic microsomesGopinath C Nallani, Appavu Chandrasekaran, Kelem Kassahun, et al.Journal of Pharmaceutical and Biomedical Analysis|March 28, 2006
Quantitation of geometric isomers of a phosphodiesterase inhibitor in rat and monkey plasma using liquid chromatography-tandem mass spectrometryYuexia Liang, Rena Zhang, Emily Adarayan, et al.Chemical Research in Toxicology|September 20, 2005
Zafirlukast metabolism by cytochrome P450 3A4 produces an electrophilic alpha,beta-unsaturated iminium species that results in the selective mechanism-based inactivation of the enzymeKelem Kassahun, Konstantine Skordos, Ian McIntosh, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 23, 2011
Pharmacokinetics and metabolism in rats, dogs, and monkeys of the cathepsin k inhibitor odanacatib: demethylation of a methylsulfonyl moiety as a major metabolic pathwayKelem Kassahun, W Cameron Black, Deborah Nicoll-Griffith, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 28, 2022
In Vitro and In Vivo Metabolism of a Novel Antimitochondrial Cancer Metabolism Agent, CPI-613, in Rat and HumanVijay Bhasker Reddy, Lakmal Boteju, Asela Boteju, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 21, 2014
Disposition and metabolism of the cathepsin K inhibitor odanacatib in humansKelem Kassahun, Ian McIntosh, Kenneth Koeplinger, et al.Pageof 2