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Journal of Medicinal Chemistry
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May 2, 2022
Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity
Preshendren Govender, Rudolf Müller, Kawaljit Singh, et al.
ACS Infectious Diseases
|
December 15, 2020
New Amidated 3,6-Diphenylated Imidazopyridazines with Potent Antiplasmodium Activity Are Dual Inhibitors of <i>Plasmodium</i> Phosphatidylinositol-4-kinase and cGMP-Dependent Protein Kinase
Peter Mubanga Cheuka, Luyanda Centani, Lauren B Arendse, et al.
ACS Infectious Diseases
|
May 30, 2020
Synthesis, Structure-Activity Relationship, and Mechanistic Studies of Aminoquinazolinones Displaying Antimycobacterial Activity
Jessica N Akester, Paul Njaria, Aloysius Nchinda, et al.
Antimicrobial Agents and Chemotherapy
|
March 10, 2022
Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones
Gregory S Basarab, Sandeep Ghorpade, Liezl Gibhard, et al.
Journal of Medicinal Chemistry
|
October 9, 2013
Structure-activity-relationship studies around the 2-amino group and pyridine core of antimalarial 3,5-diarylaminopyridines lead to a novel series of pyrazine analogues with oral in vivo activity
Yassir Younis, Frederic Douelle, Diego González Cabrera, et al.
European Journal of Medicinal Chemistry
|
April 17, 2026
Structure-Activity relationship and optimization of drug-like properties of antituberculosis 3-(4,4-dimethyl-1,4-azasilinane)methylpyrazole MmpL3 inhibitors
Lutete Peguy Khonde, Nashied Peton, Keabetswe Masike, et al.
Plos Neglected Tropical Diseases
|
September 15, 2022
Drug discovery research in Ghana, challenges, current efforts, and the way forward
Richard Kwamla Amewu, Patrick Amoateng, Patrick Kobina Arthur, et al.
Journal of Medicinal Chemistry
|
December 12, 2022
Novel 3-Trifluoromethyl-1,2,4-oxadiazole Analogues of Astemizole with Multi-stage Antiplasmodium Activity and <i>In Vivo</i> Efficacy in a <i>Plasmodium berghei</i> Mouse Malaria Infection Model
Dickson Mambwe, Constance M Korkor, Amanda Mabhula, et al.
Journal of Medicinal Chemistry
|
December 19, 2018
Structure-Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N-Aryl-3-trifluoromethyl Pyrido[1,2- a]benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria
Godfrey Mayoka, Mathew Njoroge, John Okombo, et al.
Journal of Medicinal Chemistry
|
May 12, 2025
Cell-Based Progression of Spiroindoline Phenotypic Hits Leads to the Identification of Compounds with Diverging Parasitological Profiles against the Human Malaria Parasite <i>Plasmodium falciparum</i>
Jean Dam, Grant A Boyle, André Horatscheck, et al.
Page
of 32
Search research articles
Search
Showing results (261-270 of 315) with videos related to
Sort By:
Page
of 32
Journal of Medicinal Chemistry
|
May 2, 2022
Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity
Preshendren Govender, Rudolf Müller, Kawaljit Singh, et al.
ACS Infectious Diseases
|
December 15, 2020
New Amidated 3,6-Diphenylated Imidazopyridazines with Potent Antiplasmodium Activity Are Dual Inhibitors of <i>Plasmodium</i> Phosphatidylinositol-4-kinase and cGMP-Dependent Protein Kinase
Peter Mubanga Cheuka, Luyanda Centani, Lauren B Arendse, et al.
ACS Infectious Diseases
|
May 30, 2020
Synthesis, Structure-Activity Relationship, and Mechanistic Studies of Aminoquinazolinones Displaying Antimycobacterial Activity
Jessica N Akester, Paul Njaria, Aloysius Nchinda, et al.
Antimicrobial Agents and Chemotherapy
|
March 10, 2022
Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones
Gregory S Basarab, Sandeep Ghorpade, Liezl Gibhard, et al.
Journal of Medicinal Chemistry
|
October 9, 2013
Structure-activity-relationship studies around the 2-amino group and pyridine core of antimalarial 3,5-diarylaminopyridines lead to a novel series of pyrazine analogues with oral in vivo activity
Yassir Younis, Frederic Douelle, Diego González Cabrera, et al.
European Journal of Medicinal Chemistry
|
April 17, 2026
Structure-Activity relationship and optimization of drug-like properties of antituberculosis 3-(4,4-dimethyl-1,4-azasilinane)methylpyrazole MmpL3 inhibitors
Lutete Peguy Khonde, Nashied Peton, Keabetswe Masike, et al.
Plos Neglected Tropical Diseases
|
September 15, 2022
Drug discovery research in Ghana, challenges, current efforts, and the way forward
Richard Kwamla Amewu, Patrick Amoateng, Patrick Kobina Arthur, et al.
Journal of Medicinal Chemistry
|
December 12, 2022
Novel 3-Trifluoromethyl-1,2,4-oxadiazole Analogues of Astemizole with Multi-stage Antiplasmodium Activity and <i>In Vivo</i> Efficacy in a <i>Plasmodium berghei</i> Mouse Malaria Infection Model
Dickson Mambwe, Constance M Korkor, Amanda Mabhula, et al.
Journal of Medicinal Chemistry
|
December 19, 2018
Structure-Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N-Aryl-3-trifluoromethyl Pyrido[1,2- a]benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria
Godfrey Mayoka, Mathew Njoroge, John Okombo, et al.
Journal of Medicinal Chemistry
|
May 12, 2025
Cell-Based Progression of Spiroindoline Phenotypic Hits Leads to the Identification of Compounds with Diverging Parasitological Profiles against the Human Malaria Parasite <i>Plasmodium falciparum</i>
Jean Dam, Grant A Boyle, André Horatscheck, et al.
Page
of 32