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Science Signaling|November 19, 2009
Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growthTaro Hitosugi, Sumin Kang, Matthew G Vander Heiden, et al.Blood|June 24, 2005
Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutationJason Gotlib, Caroline Berubé, Joseph D Growney, et al.Blood|February 7, 2008
High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemiaMarc M Loriaux, Ross L Levine, Jeffrey W Tyner, et al.Nature|October 17, 2008
Activating mutations in ALK provide a therapeutic target in neuroblastomaRani E George, Takaomi Sanda, Megan Hanna, et al.Cancer Cell|April 9, 2008
Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia veraGerlinde Wernig, Michael G Kharas, Rachel Okabe, et al.Blood|January 14, 2010
Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasmsNils H Thoennissen, Utz O Krug, Dhong Hyun Tony Lee, et al.Cancer Cell|February 16, 2005
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-AblEllen Weisberg, Paul W Manley, Werner Breitenstein, et al.Genes, Chromosomes & Cancer|December 8, 2007
SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patientsKenneth D Swanson, Jordan M Winter, Marcelo Reis, et al.Proceedings of the National Academy of Sciences of the United States of America|September 28, 2004
PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorderJing Chen, Daniel J Deangelo, Jeffery L Kutok, et al.Cancer Cell|December 11, 2007
Identification of driver and passenger mutations of FLT3 by high-throughput DNA sequence analysis and functional assessment of candidate allelesStefan Fröhling, Claudia Scholl, Ross L Levine, et al.Pageof 18