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Nature Communications|May 5, 2026
NCOR2 represses MHC class I molecule expression to drive metastatic progression of breast cancerPavla Ticha, Jason J Northey, Radhika Narain, et al.Developmental Cell|September 1, 2015
Adaptive Immune Regulation of Mammary Postnatal OrganogenesisVicki Plaks, Bijan Boldajipour, Jelena R Linnemann, et al.Oncoimmunology|September 19, 2017
Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophagesKelly Kersten, Seth B Coffelt, Marlous Hoogstraat, et al.Oncoimmunology|April 24, 2023
Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast tumorsOlga S Blomberg, Kevin Kos, Lorenzo Spagnuolo, et al.Oncoimmunology|March 3, 2020
Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune systemSjoerd Klarenbeek, Chris W Doornebal, Sjors M Kas, et al.The Journal of Experimental Medicine|April 1, 2025
Tumor cell heterogeneity drives spatial organization of the intratumoral immune responseMiho Tanaka, Lotus Lum, Kenneth H Hu, et al.Nature Cancer|June 3, 2024
Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironmentKevin M Tharp, Kelly Kersten, Ori Maller, et al.Nature Cell Biology|March 20, 2019
Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon responseCamilla Salvagno, Metamia Ciampricotti, Sander Tuit, et al.Cell|April 9, 2019
Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell ImmunityMikhail Binnewies, Adriana M Mujal, Joshua L Pollack, et al.Nature Medicine|April 25, 2018
Understanding the tumor immune microenvironment (TIME) for effective therapyMikhail Binnewies, Edward W Roberts, Kelly Kersten, et al.Pageof 3