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Blood Cancer Discovery|January 23, 2024
IDH1-Mutant Preleukemic Hematopoietic Stem Cells Can Be Eliminated by Inhibition of Oxidative PhosphorylationNiklas Landberg, Thomas Köhnke, Yang Feng, et al.
Blood Cancer Discovery|December 13, 2023
IDH1-mutant preleukemic hematopoietic stem cells can be eliminated by inhibition of oxidative phosphorylationNiklas Landberg, Thomas Köhnke, Yang Feng, et al.
EMBO Reports|February 14, 2022
Targeting human CALR-mutated MPN progenitors with a neoepitope-directed monoclonal antibodyDenis Tvorogov, Chloe A L Thompson-Peach, Johannes Foßelteder, et al.
Cancer Discovery|November 10, 2022
Dysregulated Lipid Synthesis by Oncogenic IDH1 Mutation Is a Targetable Synthetic Lethal VulnerabilityDaniel Thomas, Manhong Wu, Yusuke Nakauchi, et al.
Plos One|September 19, 2024
CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targetingKelly Lim, Winnie L Kan, Pramod C Nair, et al.
Leukemia|August 29, 2022
A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposureMonika M Kutyna, Chung Hoow Kok, Yoon Lim, et al.
International Journal of Molecular Sciences|June 28, 2023
Open-Spaced Ridged Hydrogel Scaffolds Containing TiO2-Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord InjuryAhad M Siddiqui, Frederic Thiele, Rachel N Stewart, et al.
Blood|January 2, 2026
Ultraprecision Therapy for Type 1 vs Type 2 CALR+ MPN by Dual Epitope Targeting that Restores Ruxolitinib SensitivityChloe Al Thompson-Peach, Daniel Thomas, Mara Dottore, et al.
Blood|March 8, 2024
IDH-mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activationLih En Hong, Mihir D Wechalekar, Monika Kutyna, et al.
Nature Communications|May 13, 2022
Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemiaMahmoud A Bassal, Saumya E Samaraweera, Kelly Lim, et al.
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