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Journal of Medicinal Chemistry
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January 17, 2014
Design, synthesis, and pharmacological evaluation of a novel series of pyridopyrazine-1,6-dione γ-secretase modulators
Martin Pettersson, Douglas S Johnson, Chakrapani Subramanyam, et al.
Medchemcomm
|
August 16, 2018
Discovery of cyclopropyl chromane-derived pyridopyrazine-1,6-dione γ-secretase modulators with robust central efficacy
Martin Pettersson, Douglas S Johnson, Danica A Rankic, et al.
ACS Medicinal Chemistry Letters
|
May 26, 2015
Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability
Martin Pettersson, Douglas S Johnson, John M Humphrey, et al.
Journal of Medicinal Chemistry
|
April 4, 2018
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation
Brian T O'Neill, Elizabeth M Beck, Christopher R Butler, et al.
Journal of Medicinal Chemistry
|
June 7, 2024
Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer's Disease
Martin Pettersson, Douglas S Johnson, John M Humphrey, et al.
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Search research articles
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Showing results (61-70 of 65) with videos related to
Sort By:
Page
of 7
You have reached the last page of results.
This site can display upto 65 results.
Journal of Medicinal Chemistry
|
January 17, 2014
Design, synthesis, and pharmacological evaluation of a novel series of pyridopyrazine-1,6-dione γ-secretase modulators
Martin Pettersson, Douglas S Johnson, Chakrapani Subramanyam, et al.
Medchemcomm
|
August 16, 2018
Discovery of cyclopropyl chromane-derived pyridopyrazine-1,6-dione γ-secretase modulators with robust central efficacy
Martin Pettersson, Douglas S Johnson, Danica A Rankic, et al.
ACS Medicinal Chemistry Letters
|
May 26, 2015
Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability
Martin Pettersson, Douglas S Johnson, John M Humphrey, et al.
Journal of Medicinal Chemistry
|
April 4, 2018
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation
Brian T O'Neill, Elizabeth M Beck, Christopher R Butler, et al.
Journal of Medicinal Chemistry
|
June 7, 2024
Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer's Disease
Martin Pettersson, Douglas S Johnson, John M Humphrey, et al.
Page
of 7