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Ken Grime

Showing results (1-10 of 35) with videos related to

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Drug Discovery Today. Technologies|July 2, 2014
Metabolic screening in vitro: metabolic stability, CYP inhibition and inductionRobert J Riley, Ken Grime
Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 10, 2012
Species differences in biliary clearance and possible relevance of hepatic uptake and efflux transporters involvementKen Grime, Stuart W Paine
Current Drug Metabolism|February 4, 2012
Optimisation of DMPK by the inhaled route: challenges and approachesAnne E Cooper, Douglas Ferguson, Ken Grime
Expert Opinion on Drug Metabolism & Toxicology|February 3, 2007
Time-dependent CYP inhibitionRobert J Riley, Ken Grime, Richard Weaver
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 29, 2005
Automated assessment of time-dependent inhibition of human cytochrome P450 enzymes using liquid chromatography-tandem mass spectrometry analysisAnthony Atkinson, Jane R Kenny, Ken Grime
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 23, 2019
Plasma Protein Binding as an Optimizable Parameter for Acidic DrugsPhilip Gardiner, Rhona J Cox, Ken Grime
Current Drug Metabolism|January 7, 2011
The use of HepaRG and human hepatocyte data in predicting CYP induction drug-drug interactions via static equation and dynamic mechanistic modelling approachesKen Grime, Douglas D Ferguson, Robert J Riley
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 1, 2013
Predicting metabolic clearance for drugs that are actively transported into hepatocytes: incubational binding as a consequence of in vitro hepatocyte concentration is a key factorPär Nordell, Petter Svanberg, James Bird, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 14, 2008
Functional consequences of active hepatic uptake on cytochrome P450 inhibition in rat and human hepatocytesKen Grime, Peter J H Webborn, Robert J Riley
Journal of Medicinal Chemistry|April 24, 2025
In Vitro ADME Profiling of PROTACs: Successes, Challenges, and Lessons Learned from Analysis of Clinical PROTACs from a Diverse Physicochemical SpaceAbhishek Srivastava, Andy Pike, Magda Swedrowska, et al.
Pageof 4

Showing results (1-10 of 35) with videos related to

Sort By:
Pageof 4
Drug Discovery Today. Technologies|July 2, 2014
Metabolic screening in vitro: metabolic stability, CYP inhibition and inductionRobert J Riley, Ken Grime
Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 10, 2012
Species differences in biliary clearance and possible relevance of hepatic uptake and efflux transporters involvementKen Grime, Stuart W Paine
Current Drug Metabolism|February 4, 2012
Optimisation of DMPK by the inhaled route: challenges and approachesAnne E Cooper, Douglas Ferguson, Ken Grime
Expert Opinion on Drug Metabolism & Toxicology|February 3, 2007
Time-dependent CYP inhibitionRobert J Riley, Ken Grime, Richard Weaver
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 29, 2005
Automated assessment of time-dependent inhibition of human cytochrome P450 enzymes using liquid chromatography-tandem mass spectrometry analysisAnthony Atkinson, Jane R Kenny, Ken Grime
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 23, 2019
Plasma Protein Binding as an Optimizable Parameter for Acidic DrugsPhilip Gardiner, Rhona J Cox, Ken Grime
Current Drug Metabolism|January 7, 2011
The use of HepaRG and human hepatocyte data in predicting CYP induction drug-drug interactions via static equation and dynamic mechanistic modelling approachesKen Grime, Douglas D Ferguson, Robert J Riley
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 1, 2013
Predicting metabolic clearance for drugs that are actively transported into hepatocytes: incubational binding as a consequence of in vitro hepatocyte concentration is a key factorPär Nordell, Petter Svanberg, James Bird, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 14, 2008
Functional consequences of active hepatic uptake on cytochrome P450 inhibition in rat and human hepatocytesKen Grime, Peter J H Webborn, Robert J Riley
Journal of Medicinal Chemistry|April 24, 2025
In Vitro ADME Profiling of PROTACs: Successes, Challenges, and Lessons Learned from Analysis of Clinical PROTACs from a Diverse Physicochemical SpaceAbhishek Srivastava, Andy Pike, Magda Swedrowska, et al.
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