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Ken Yamada

Showing results (31-40 of 52) with videos related to

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Nucleic Acids Research|May 10, 2024
A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous systemJillian Belgrad, Qi Tang, Sam Hildebrand, et al.
Biorxiv : the Preprint Server for Biology|January 8, 2024
A programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous systemJillian Belgrad, Qi Tang, Sam Hildebrand, et al.
Brain Communications|September 10, 2025
Mutant huntingtin exon 1 protein detected in mouse brain with neoepitope antibody: effects of CAG repeat expansion, MutS Homolog 3 silencing and aggregationEllen Sapp, Adel Boudi, Andrew Iwanowicz, et al.
Nucleic Acids Research|December 1, 2021
Structurally constrained phosphonate internucleotide linkage impacts oligonucleotide-enzyme interaction, and modulates siRNA activity and allele specificityKen Yamada, Samuel Hildebrand, Sarah M Davis, et al.
Molecular Therapy. Nucleic Acids|September 5, 2024
Identification of selective and non-selective <i>C9ORF72</i> targeting <i>in vivo</i> active siRNAsJames W Gilbert, Zachary Kennedy, Bruno M D C Godinho, et al.
Journal of Medicinal Chemistry|October 17, 2017
Discovery of a Novel Piperidine-Based Inhibitor of Cholesteryl Ester Transfer Protein (CETP) That Retains Activity in Hypertriglyceridemic PlasmaKen Yamada, Margaret Brousseau, Wataru Honma, et al.
Nature Communications|October 3, 2022
Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington's disease modelsFaith Conroy, Rachael Miller, Julia F Alterman, et al.
Research Square|June 29, 2026
Precision RNAi for Fibrodysplasia Ossificans Progressiva: a combinatorial, unimolecular, allele selective approachJaeHyuck Shim, Yeon-Suk Yang, Katherine Gross, et al.
Research Square|July 3, 2023
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivoVignesh Narayan Hariharan, Jillian Caiazzi, Rachael Miller, et al.
Nucleic Acids Research|December 23, 2025
Potent and durable gene modulation in heart and muscle with chemically defined lipophilic siRNAsHassan H Fakih, Clemens Lochmann, Rosemary Gagnon, et al.
Pageof 6

Showing results (31-40 of 52) with videos related to

Sort By:
Pageof 6
Nucleic Acids Research|May 10, 2024
A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous systemJillian Belgrad, Qi Tang, Sam Hildebrand, et al.
Biorxiv : the Preprint Server for Biology|January 8, 2024
A programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous systemJillian Belgrad, Qi Tang, Sam Hildebrand, et al.
Brain Communications|September 10, 2025
Mutant huntingtin exon 1 protein detected in mouse brain with neoepitope antibody: effects of CAG repeat expansion, MutS Homolog 3 silencing and aggregationEllen Sapp, Adel Boudi, Andrew Iwanowicz, et al.
Nucleic Acids Research|December 1, 2021
Structurally constrained phosphonate internucleotide linkage impacts oligonucleotide-enzyme interaction, and modulates siRNA activity and allele specificityKen Yamada, Samuel Hildebrand, Sarah M Davis, et al.
Molecular Therapy. Nucleic Acids|September 5, 2024
Identification of selective and non-selective <i>C9ORF72</i> targeting <i>in vivo</i> active siRNAsJames W Gilbert, Zachary Kennedy, Bruno M D C Godinho, et al.
Journal of Medicinal Chemistry|October 17, 2017
Discovery of a Novel Piperidine-Based Inhibitor of Cholesteryl Ester Transfer Protein (CETP) That Retains Activity in Hypertriglyceridemic PlasmaKen Yamada, Margaret Brousseau, Wataru Honma, et al.
Nature Communications|October 3, 2022
Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington's disease modelsFaith Conroy, Rachael Miller, Julia F Alterman, et al.
Research Square|June 29, 2026
Precision RNAi for Fibrodysplasia Ossificans Progressiva: a combinatorial, unimolecular, allele selective approachJaeHyuck Shim, Yeon-Suk Yang, Katherine Gross, et al.
Research Square|July 3, 2023
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivoVignesh Narayan Hariharan, Jillian Caiazzi, Rachael Miller, et al.
Nucleic Acids Research|December 23, 2025
Potent and durable gene modulation in heart and muscle with chemically defined lipophilic siRNAsHassan H Fakih, Clemens Lochmann, Rosemary Gagnon, et al.
Pageof 6