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Nature Communications|June 29, 2026
Nos1 neurons in the paraventricular hypothalamic area modulate lipid metabolism via the sympathetic nervous system in male miceKunio Kondoh, Emi Hashiuchi, Yuka Inaba, et al.Scientific Reports|August 12, 2015
Identification of key neoculin residues responsible for the binding and activation of the sweet taste receptorTaichi Koizumi, Tohru Terada, Ken-ichiro Nakajima, et al.Plos One|May 12, 2011
Identification and modulation of the key amino acid residue responsible for the pH sensitivity of neoculin, a taste-modifying proteinKen-ichiro Nakajima, Kanako Yokoyama, Taichi Koizumi, et al.Applied and Environmental Microbiology|May 5, 2006
Extracellular production of neoculin, a sweet-tasting heterodimeric protein with taste-modifying activity, by Aspergillus oryzaeKen-ichiro Nakajima, Tomiko Asakura, Jun-ichi Maruyama, et al.Nature Communications|October 10, 2019
Hypothalamic neuronal circuits regulating hunger-induced taste modificationOu Fu, Yuu Iwai, Masataka Narukawa, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|February 12, 2008
Acid-induced sweetness of neoculin is ascribed to its pH-dependent agonistic-antagonistic interaction with human sweet taste receptorKen-ichiro Nakajima, Yuji Morita, Ayako Koizumi, et al.Nature Communications|January 9, 2016
Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intakeKen-ichiro Nakajima, Zhenzhong Cui, Chia Li, et al.Journal of Agricultural and Food Chemistry|June 10, 2008
Biochemical and genomic analysis of neoculin compared to monocot mannose-binding lectinsAkiko Shimizu-Ibuka, Yuji Nakai, Keisuke Nakamori, et al.Cellular and Molecular Gastroenterology and Hepatology|October 12, 2025
Barrington's Nucleus: A Pontine Defecation Brain Area Exhibiting Prompt and Delayed Defecation ResponsesKota Bussaka, Yoshimasa Tanaka, Kunio Kondoh, et al.Biochemical and Biophysical Research Communications|June 27, 2007
Microbial production of sensory-active miraculinKeisuke Ito, Tomiko Asakura, Yuji Morita, et al.Pageof 4